921623-31-6

Basic information

• Product Name: 4-(4,4,4-Trifluorobutoxy)Benzoic Acid
• Synonyms: 4-(4,4,4-Trifluorobutoxy)Benzoic Acid;4-(4,4,4-Trifluorobutoxy)Benzoic Acid(WXC03646)
• CAS NO: 921623-31-6
• Molecular Formula: C₁₁H₁₁F₃O₃
• Molecular Weight: 248.1984496
• Mol File: 921623-31-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(4,4,4-Trifluorobutoxy)Benzoic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4,4,4-Trifluorobutoxy)Benzoic Acid(921623-31-6)
• EPA Substance Registry System: 4-(4,4,4-Trifluorobutoxy)Benzoic Acid(921623-31-6)

Safety Data

• Hazardous Substances Data: 921623-31-6(Hazardous Substances Data)

Usage

Description

4-(4,4,4-trifluorobutoxy)benzoic acid, also known as TFBA, is a chemical compound with the molecular formula C11H11F3O3. It is a white crystalline powder that is insoluble in water but soluble in organic solvents. TFBA is known for its high thermal stability and has applications in the development of liquid crystals and other materials.

Uses

Used in Pharmaceutical and Agrochemical Industries:
TFBA is used as a building block in the synthesis of pharmaceuticals and agrochemicals. It acts as a carboxylic acid derivative and is often used as a reagent in organic chemistry reactions.
Used in Material Science:
TFBA has applications in the development of liquid crystals and other materials due to its high thermal stability.
Used in Organic Chemistry:
TFBA is often used as a reagent in organic chemistry reactions, contributing to the synthesis of various compounds.
Used in Research:
TFBA has been studied for its potential anti-inflammatory and anti-cancer properties, indicating its potential use in medical research and development.

Upstream product

• 120-47-8 Ethyl 4-hydroxybenzoate 
• 99-76-3 methyl 4-hydroxylbenzoate 
• 1413947-89-3 methyl 4-(4,4,4-trifluoro-butoxy)-benzoate 
• 1194-02-1 4-fluorobenzonitrile 

Downstream Products

• 942624-57-9 6-{[((2E)-3-{4-[(4-(4,4,4-trifluorobutoxy)benzoy)oxy]phenyl}prop-2-enoyl)oxy]}hexyl 3,5-dinitrobenzoate 
• 942624-54-6 4-formylphenyl-4-(4,4,4-trifluorobutoxy)benzoate 
• 1345471-42-2 2-[4-(4,4,4-trifluorobutoxy)phenyl]-5,6-dihydro-4H-1,3-dithiin-1-ium trifluoromethanesulfonate 
• 1345475-50-4 6-[((2E)-3-(4-{difluoro[4-(4,4,4-trifluorobutoxy)phenyl]methoxy}phenyl)-prop-2-enoyl)oxy]hexyl 3,5-dinitrobenzoate 
• 1345474-84-1 3,5-diaminobenzyl (2E)-3-(4-{difluoro[4-(4,4,4-trifluorobutoxy)phenyl]-methoxy}phenyl)prop-2-enoate 
• 1345474-83-0 3,5-dinitrobenzyl (2E)-3-(4-{difluoro[4-(4,4,4-trifluorobutoxy)phenyl]-methoxy}phenyl)prop-2-enoate 
• 1345472-52-7 2-(2,4-diaminophenyl)ethyl (2E)-3-(4-{difluoro[4-(4,4,4-trifluorobutoxy)-phenyl]methoxy}phenyl)prop-2-enoate 
• 1345472-51-6 2-(2,4-dinitrophenyl)ethyl (2E)-3-(4-{difluoro[4-(4,4,4-trifluorobutoxy)phenyl]-methoxy}-phenyl)prop-2-enoate 
• 1345471-52-4 (2E)-3-(4-{difluoro[4-(4,4,4-trifluorobutoxy)phenyl]methoxy}phenyl)prop-2-enoic acid 
• 1345471-49-9 methyl (2E)-3-(4-{difluoro[4-(4,4,4-trifluorobutoxy)phenyl]methoxy}phenyl)-prop-2-enoate 
• 1345471-44-4 1-bromo-4-{difluoro[4-(4,4,4-trifluorobutoxy)phenyl]methoxy}benzene 
• 1345477-32-8 2,2-bis(4-nitrobenzyl)-3-{[(2E)-3-(4-{difluoro[4-(4,4,4-trifluorobutoxy)phenyl]methoxy}phenyl)prop-2-enoyl]oxy}propyl (2E)-3-(4-{difluoro[4-(4,4,4-trifluorobutoxy)phenyl]methoxy}phenyl)prop-2-enoate 
• 1345477-13-5 [4,4'-diamino-2'-({[(2E)-3-(4-{difluoro[4-(4,4,4-trifluorobutoxy)phenyl]methoxy}phenyl)prop-2-enoyl]oxy}methyl)-1,1'-biphenyl-2-yl]methyl (2E)-3-(4-{difluoro[4-(4,4,4-trifluorobutoxy)phenyl]methoxy}phenyl)prop-2-enoate 
• 1345477-12-4 [4,4'-dinitro-2'-({[(2E)-3-(4-{difluoro[4-(4,4,4-trifluorobutoxy)phenyl]methoxy}phenyl)prop-2-enoyl]oxy}methyl)-1,1'-biphenyl-2-yl]methyl (2E)-3-(4-{difluoro[4-(4,4,4-trifluorobutoxy)phenyl]methoxy}phenyl)prop-2-enoate 

Relevant articles and documents

Amine compound and process for preparation thereof, liquid crystal aligning, liquid crystal alignment film, the liquid crystal display element (by machine translation)

The present invention relates to an amine compound, a method for preparing same, and a liquid crystal alignment agent, a liquid crystal alignment film, and a liquid crystal display device, having same. A liquid crystal alignment agent having polyamic acid or polyimide prepared using the amine compound of the present invention enables a liquid crystal alignment film and a liquid crystal display device having excellent thermal stability even after forming the liquid crystal alignment film, and expressing high alignment and stability even after an ultraviolet ray irradiation.

Flavones as isosteres of 4(1H)-quinolones: Discovery of ligand efficient and dual stage antimalarial lead compounds

Malaria is responsible for nearly one million deaths annually, and the increasing prevalence of multi-resistant strains of Plasmodium falciparum poses a great challenge to controlling the disease. A diverse set of flavones, isosteric to 4(1H)-quinolones, were prepared and profiled for their antiplasmodial activity against the blood stage of P. falciparum W2 strain, and the liver stage of the rodent parasite Plasmodium berghei. Ligand efficient leads were identified as dual stage antimalarials, suggesting that scaffold optimization may afford potent antiplasmodial compounds.

SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

It is an object of the present invention to provide a substituted propanamide derivative or a pharmacologically acceptable salt thereof that is useful as a prophylactic or therapeutic agent for a bone metabolic disease. The present invention relates to a pharmaceutical composition comprising a compound having General Formula (I) or a pharmacologically acceptable salt thereof as an active ingredient: [wherein, R1 represents a C6-C10 aryl group that may be substituted by a group selected from Substituent Group α, for example; R2 represents a C6-C10aryl group that may be substituted by a group selected from Substituent Group α, for example; and X represents a hydroxyl group or a C1-C6 alkoxy group, for example].