922500-93-4

Basic information

• Product Name: oxetan-3-ylidene-acetaldehyde
• Synonyms: oxetan-3-ylidene-acetaldehyde;2-(3-Oxetanylidene)acetaldehyde;Acetaldehyde, 2-(3-oxetanylidene)-;2-(oxetan-3-ylidene)acetaldehyde
• CAS NO: 922500-93-4
• Molecular Formula: C₅H₆O₂
• Molecular Weight: 98
• Mol File: 922500-93-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 199℃
• Flash Point: 90℃
• Appearance: /
• Density: 1.281
• Vapor Pressure: 0.352mmHg at 25°C
• Refractive Index: 1.609
• Storage Temp.: 2-8°C
• CAS DataBase Reference: oxetan-3-ylidene-acetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: oxetan-3-ylidene-acetaldehyde(922500-93-4)
• EPA Substance Registry System: oxetan-3-ylidene-acetaldehyde(922500-93-4)

Safety Data

• Hazardous Substances Data: 922500-93-4(Hazardous Substances Data)

Usage

General Description

Oxetan-3-ylidene-acetaldehyde is a chemical compound with the molecular formula C5H6O3. It falls under the category of heterocyclic organic compounds, specifically, it's an oxetane. oxetan-3-ylidene-acetaldehyde has a structure consisting of a four-membered cyclic ether ring with a carbonyl group (-C=O) attached. Due to the presence of this carbonyl group, it has the properties of an aldehyde, a type of organic compound that is often used in the production of resins and plastics. The specific properties and uses of oxetan-3-ylidene-acetaldehyde, however, may vary and largely depend on its arrangements and interactions with other atoms or molecules.

InChI:InChI=1/C5H6O2/c6-2-1-5-3-7-4-5/h1-2H,3-4H2

Upstream product

• 6704-31-0 oxetan-3-one 
• 2136-75-6 (triphenylphosphoranylidene)acetaldehyde 

Downstream Products

• 922501-06-2 [3-(4-tert-butyl-phenyl)-oxetan-3-yl]-acetaldehyde 

Relevant articles and documents

Synergistic Catalysis for the Asymmetric [3+2] Cycloaddition of Vinyl Aziridines with α,β-Unsaturated Aldehydes

The first asymmetric [3+2] cycloaddition of vinyl aziridines with α,β-unsaturated aldehydes, based on synergistic catalysis, is disclosed. This methodology allows the formation of attractive pyrrolidine structures in good yields (up to 84 %), moderate diastereoselectivity, and high enantioselectivity values (up to >99 % ee). Additionally, a tricyclic pyrrolidine core structure found in biologically active molecules was synthesized in a one-pot fashion by using the presented reaction concept. Finally, a mechanistic proposal is outlined.

Oxetanes as promising modules in drug discovery

(Chemical Equation Presented) Ring the changes: Introduction of an oxetane ring results in remarkably improved physico- and biochemical properties of the underlying scaffold. The oxetane ring confers enhanced solubility, reduces the metabolic degredation, lipophilicity, and amphiphilicity, and modulates the basicity of a nearby amine group.