922524-99-0

Basic information

• Product Name: Pyrazine, 2-(4-methylphenyl)-, 1-oxide
• CAS NO: 922524-99-0
• Molecular Formula: C11H10N2O
• Molecular Weight: 186.213
• Mol File: 922524-99-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Pyrazine, 2-(4-methylphenyl)-, 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrazine, 2-(4-methylphenyl)-, 1-oxide(922524-99-0)
• EPA Substance Registry System: Pyrazine, 2-(4-methylphenyl)-, 1-oxide(922524-99-0)

Safety Data

• Hazardous Substances Data: 922524-99-0(Hazardous Substances Data)

Upstream product

• 694-59-7 pyridine N-oxide 
• 2423-65-6 Pyrazin-N-Oxid(PyzNO) 
• 106-38-7 para-bromotoluene 
• 29540-83-8 p-tolyl triflate 
• 624-31-7 4-tolyl iodide 

Downstream Products

• 637352-85-3 2-chloro-6-p-tolylpyrazine 
• 65709-31-1 (RS)-2-(4-methylphenyl)piperazine 
• 108030-80-4 2-(4-methylphenyl)pyrazine 

Relevant articles and documents

Mechanistic analysis of azine N-oxide direct arylation: Evidence for a critical role of acetate in the Pd(OAc)2 precatalyst

Detailed mechanistic studies on the palladium-catalyzed direct arylation of pyridine N-oxides are presented. The order of each reaction component is determined to provide a general mechanistic picture. The C-H bond cleaving step is examined in further det

Use of N-oxide compounds in coupling reactions

Metal-catalyzed coupling process comprising reacting a compound of general formula 1 with a compound A-X, to obtain a compound of general formula 2, which may further be converted to a compound of general formula 3