92335-48-3

Basic information

• Product Name: 2-Benzothiazolesulfinicacid,methylester(6CI,7CI,9CI)
• Synonyms: 2-Benzothiazolesulfinicacid,methylester(6CI,7CI,9CI)
• CAS NO: 92335-48-3
• Molecular Formula: C8H7NO2S2
• Molecular Weight: 213.27668
• Product Categories: BENZOTHIAZOLE
• Mol File: 92335-48-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Benzothiazolesulfinicacid,methylester(6CI,7CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzothiazolesulfinicacid,methylester(6CI,7CI,9CI)(92335-48-3)
• EPA Substance Registry System: 2-Benzothiazolesulfinicacid,methylester(6CI,7CI,9CI)(92335-48-3)

Safety Data

• Hazardous Substances Data: 92335-48-3(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 120-78-5 di(benzothiazol-2-yl)disulfide 

Downstream Products

• 2655-38-1 N-benzylbenzo[d]thiazole-2-sulfonamide 
• 21816-82-0 N-benzyl-2-aminobenzo[d]thiazole 
• 878376-34-2 1,3-benzothiazole-2-sulfonyl fluoride 
• 95-16-9 1,3-Benzothiazole 

Relevant articles and documents

Unified Approach to Benzo[ d]thiazol-2-yl-Sulfonamides

In this paper, we report a unified approach to N-substituted and N,N-disubstituted benzothiazole (BT) sulfonamides. Our approach to BT-sulfonamides starts from simple commercially available building blocks (benzo[d]thiazole-2-thiol and primary and secondary amines) that are connected via (a) a S oxidation/S-N coupling approach, (b) a S-N coupling/S-oxidation sequence, or via (c) a S-oxidation/S-F bond formation/SuFEx approach. The labile N-H bond in N-monoalkylated BT-sulfonamides (pKa (BTSO2N(H)Bn) = 3.34 ± 0.05) further allowed us to develop a simple weak base-promoted N-alkylation method and a stereoselective microwave-promoted Fukuyama-Mitsunobu reaction. N-Alkyl-N-aryl BT-sulfonamides were accessed with the help of the Chan-Lam coupling reaction. Developed methods were further used in stereo and chemoselective transformations of podophyllotoxin and several amino alcohols.