92352-29-9

Basic information

• Product Name: 5-PYRIDIN-2-YL-2H-PYRAZOL-3-YLAMINE
• Synonyms: TIMTEC-BB SBB010423;5-PYRIDIN-2-YL-2H-PYRAZOL-3-YLAMINE;ASINEX-REAG BAS 10149532;CHEMBRDG-BB 4010182;5-(PYRIDIN-2-YL)-1H-PYRAZOL-3-AMINE;5-Amino-3-(pyrid-2-yl)-1H-pyrazole;5-(yridine-2-yl)-1H-pyrazol-3-amine;1H-Pyrazol-3-amine, 5-(2-pyridinyl)-
• CAS NO: 92352-29-9
• Molecular Formula: C₈H₈N₄
• Molecular Weight: 160.18
• Mol File: 92352-29-9.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 471.1°C at 760 mmHg
• Flash Point: 270°C
• Appearance: /
• Density: 1.315g/cm³
• Vapor Pressure: 4.79E-09mmHg at 25°C
• Refractive Index: 1.673
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 5-PYRIDIN-2-YL-2H-PYRAZOL-3-YLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-PYRIDIN-2-YL-2H-PYRAZOL-3-YLAMINE(92352-29-9)
• EPA Substance Registry System: 5-PYRIDIN-2-YL-2H-PYRAZOL-3-YLAMINE(92352-29-9)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 92352-29-9(Hazardous Substances Data)

Usage

General Description

5-Pyridin-2-yl-2H-pyrazol-3-ylamine is an organic chemical compound consisting of a pyridine ring and a pyrazole ring with an amine group attached. It is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 5-PYRIDIN-2-YL-2H-PYRAZOL-3-YLAMINE has the potential to be used as a building block in the development of new drugs, as it can be modified to create molecules with specific biological activities. Its unique structure and properties make it a valuable tool in the field of medicinal chemistry and drug discovery. Additionally, it can also be used in research and development for the synthesis of novel compounds with potential therapeutic applications.

InChI:InChI=1/C8H8N4/c9-8-5-7(11-12-8)6-3-1-2-4-10-6/h1-5H,(H3,9,11,12)

Upstream product

• 2524-52-9 ethyl-2-picolinate 
• 98-98-6 2-Picolinic acid 
• 54123-21-6 3-(pyridine-2-yl)-3-oxopropanenitrile 

Downstream Products

• 1433787-05-3 N¹,N³-bis(3-(pyridin-2-yl)-1H-pyrazole-5-yl)isophthalamide 
• 1028842-42-3 5-(2,3-difluoro-phenylsulfanylmethyl)-2-pyridin-2-yl-pyrazolo[1,5-a]pyrimidin-7-ol 
• 1610948-36-1 N¹,N³,N⁵-tris(3-(pyridin-2-yl)-1H-pyrazol-5-yl)benzene-1,3,5-tricarboxamide 
• 1232220-49-3 N-(3-methyl-benzylidene)-N'-(7-morpholin-4-yl-2-pyridin-2-yl-pyrazolo[1,5-a]pyrimidin-5-yl)-hydrazine 

Relevant articles and documents

FUSED TRICYCLIC HETEROCYCLIC COMPOUNDS AS INHIBITORS OF PIKFYVE KINASE USEFUL FOR THE TREATMENT OF NEUROLOGICAL DISEASES

The present disclosure provides compounds that are inhibitors of PIKfyve and/or PI3 kinases, and are therefore useful for the treatment of neurological diseases that are treatable by inhibition of PIKfyve. Also provided are pharmaceutical compositions containing such compounds, and methods of treatment using such compounds.

5- OR 7-AZAINDAZOLES AS BETA-LACTAMASE INHIBITORS

The present invention relates to β-lactamase inhibitors having the following general formula (I): wherein R1-R4 and X1-X2 are defined in the specification, pharmaceutical composition thereof, and use thereof for the treatment of a bacterial infection, alone or in combination with β-lactam antibiotics and/or other antibiotics and/or other β-lactamase inhibitors.

MULTISUBSTITUTED AROMATIC COMPOUNDS AS SERINE PROTEASE INHIBITORS

There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of kallikrein.