924296-18-4 Usage
General Description
9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 9-[(phenylmethoxy)imino]- is a chemical compound with the molecular formula C23H12N4O. It is a derivative of the indeno[1,2-b]pyrazine class of compounds, which are known for their potential pharmacological and biological activities. The presence of the phenylmethoxy group in the 9-position of the indeno[1,2-b]pyrazine ring adds to its chemical properties and potential applications. 9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 9-[(phenylmethoxy)imino]- may be of interest for further study in medicinal chemistry and drug discovery due to its unique structure and potential biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 924296-18-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,4,2,9 and 6 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 924296-18:
(8*9)+(7*2)+(6*4)+(5*2)+(4*9)+(3*6)+(2*1)+(1*8)=184
184 % 10 = 4
So 924296-18-4 is a valid CAS Registry Number.
InChI:InChI=1/C20H11N5O/c21-10-16-17(11-22)24-20-18(23-16)14-8-4-5-9-15(14)19(20)25-26-12-13-6-2-1-3-7-13/h1-9H,12H2
924296-18-4Relevant articles and documents
Synthesis and biological evaluation of 9-oxo-9hindeno[1,2-b]pyrazine-2,3- dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes
Colombo, Matteo,Vallese, Stefania,Peretto, Ilaria,Jacq, Xavier,Rain, Jean-Christophe,Colland, Frederic,Guedat, Philippe
experimental part, p. 552 - 558 (2010/12/25)
High-throughput screening highlighted 9-oxo-9H-indeno[1,2-b]pyrazine-2,3- dicarbonitrile (1) as an active inhibitor of ubiquitin-specific proteases (USPs), a family of hydrolytic enzymes involved in the removal of ubiquitin from protein substrates. The chemical behavior of compound 1 was examined. Moreover, the synthesis and in vitro evaluation of new compounds, analogues of 1, led to the identification of potent and selective inhibitors of the deubiquitinating enzyme USP8.
