925-47-3

Basic information

• Product Name: DIETHYL THIOGLYCOLATE 96
• Synonyms: DIETHYL THIOGLYCOLATE 96;aceticacid,2,2’-thiobis-,diethylester;bis(carbethoxymethyl)sulfide;thiodiaceticacid,diethylester;3-Thiaglutaric acid diethyl ester, Diethyl 2,2μ-thiodiacetate;2,2'-Thiobis(acetic acid ethyl) ester;Diethyl 2,2'-thiodiacetate;2-Mercapto-butyricacidethylester
• CAS NO: 925-47-3
• Molecular Formula: C₈H₁₄O₄S
• Molecular Weight: 206.25936
• EINECS: 213-117-9
• Product Categories: Building Blocks;C8 to C9;Carbonyl Compounds;Chemical Synthesis;Esters;Organic Building Blocks
• Mol File: 925-47-3.mol
• Article Data: 22

Chemical Properties

• Melting Point: 69-72 °C(lit.)
• Boiling Point: 252-253 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.146 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0115mmHg at 25°C
• Refractive Index: n20/D 1.467(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: DIETHYL THIOGLYCOLATE 96(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYL THIOGLYCOLATE 96(925-47-3)
• EPA Substance Registry System: DIETHYL THIOGLYCOLATE 96(925-47-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 925-47-3(Hazardous Substances Data)

Usage

Uses

Diethyl 2,?2''-?Thiodiacetate is used in the synthesis of potent anticonvulsant agents. As well, used in the preparation of thienophenanthrene derivatives as polymer light-emitting devices and solar ccells.

InChI:InChI=1/C8H14O4S/c1-3-11-7(9)5-13-6-8(10)12-4-2/h3-6H2,1-2H3

Upstream product

• 123-93-3 thiodiacetic acid 
• 105-36-2 ethyl bromoacetate 
• 623-51-8 ethyl 2-sulfanylacetate 
• 5187-82-6 (ethoxycarbonylmethyl)dimethylsulfonium bromide 
• 105-39-5 chloroacetic acid ethyl ester 
• 4455-13-4 methylthioacetic acid ethyl ester 
• 13001-80-4 bis-(2-chloro-2-ethoxy-vinyl)-sulfane 
• 623-73-4 diazoacetic acid ethyl ester 
• 64-17-5 ethanol 

Downstream Products

• 1822-66-8 3,4-dihydroxythiophene-2,5-dicarboxylic acid diethyl ester 
• 19799-42-9 3,4-bis(phenyl)thiophene-2,5-dicarboxylic acid 
• 977-57-1 5-(ethoxycarbonyl)-3,4-diphenylthiophene-2-carboxylic acid 
• 18361-03-0 3,4-ethylenedioxythiophene-2,5-dicarboxyllic acid 
• 1332863-62-3 N-nitroso-2,6-dicarbethoxy-3,5-diphenyltetrahydro-1,4-thiazine-1,1-dioxide 

Relevant articles and documents

Synthesis of 2,6-dicarbethoxy-3,5-diaryltetrahydro-1,4-thiazine-1,1-dioxide derivatives as potent anticonvulsant agents

Abstract An efficient synthesis of 2,6-dicarbethoxy-3,5-diaryltetrahydro-1,4-thiazine-1,1-dioxide derivatives has been achieved under aqueous medium for the first time in good to excellent yields. All the synthesized compounds were tested for anticonvulsant activity using the maximal electroshock (MES), subcutaneous pentylenetetrazole (scPTZ) screens, which are the most broadly employed seizure models for early identification of candidate anticonvulsants. Their neurotoxicity was determined applying the rotarod test. Seven compounds 4a, 4d, 4f, 4h, 4o, 4p and 4q showed promising anticonvulsant activities in both models employed for anticonvulsant evaluation. The most active compound 4d showed the MES-induced seizures with ED50 value of 10.2 mg/kg and TD50 value of 288.6 mg/kg after intraperitoneal injection to mice, which provided compound 4d with a protective index (TD50/ED50) of 28.3 in the MES test.

Aminothiophene sulfonic acid ester

PROBLEM TO BE SOLVED: To provide 3,4-disubstituted thiophene sulfonate usable as a monomer for a conductive polymer, and not having carboxylate on 2,5-positions, and to provide a method for producing the same.SOLUTION: This thiophene sulfonate is represented by general formula (1). The thiophene sulfonate is obtained, for example, by decarboxylation of 3,4-dihydroxy-2,5-dicarboxylic acid thiophene in a basic inert solvent, followed by reaction with sulfonyl chlorides in the presence of a tertiary alkylamine catalyst. (In the formula, Rand Reach independently represent a 1-8C alkyl, phenyl or tolyl).

Preparation of an EDOT-based polymer: Optoelectronic properties and electrochromic device application

Here we present the synthesis, characterization and electropolymerization of a new EDOT-based monomer; 5,10-dihydrobenzo[f]thieno[3,4-b][1,4]dioxocine (DTD). Electrochemical polymerization of DTD was performed potentiostatically by using dichloromethane (DCM) as solvent and tetrabutylammonium hexafluorophosphate (TBPF6) as supporting electrolyte. Homopolymer [P(DTD)] films and copolymer [P(DTD-co-TPA)] films of DTD prepared by using 4-(2,5-di(thiophen-2-yl)-1H-pyrrole-1-yl)butane-1-amine (TPA) were characterized via CV and UV-vis spectroscopy. Spectroelectrochemical analysis of P(DTD) revealed electronic transitions at 585 nm (π-π transition) with an electronic band gap of 1.69 eV. Electrochromic studies revealed that P(DTD) has competitive properties to EDOT. Furthermore, a dual-type complementary colored polymer electrochromic device based on P(DTD) and P(TPA) was constructed in sandwich configuration. Spectroelectrochemical studies revealed that the oxidized state of the device shows a blue color whereas it is yellow in the reduced state. The maximum contrast (Δ%T) and switching time of the device were measured as 25.5% and 0.5 s for 385 nm and 21% and 1.0 s for 550 nm.