925685-10-5Relevant articles and documents
Linking bisphosphonates to the free amino groups in fluoroquinolones: Preparation of osteotropic prodrugs for the prevention of osteomyelitis
Houghton, Tom J.,Tanaka, Kelly S. E.,Kang, Ting,Dietrich, Evelyne,Lafontaine, Yanick,Delorme, Daniel,Ferreira, Sandra S.,Viens, Frederic,Arhin, Francis F.,Sarmiento, Ingrid,Lehoux, Dario,Fadhil, Ibtihal,Laquerre, Karine,Liu, Jing,Ostiguy, Valérie,Poirier, Hugo,Moeck, Gregory,Parr Jr., Thomas R.,Far, Adel Rafai
experimental part, p. 6955 - 6969 (2009/11/30)
Osteomyelitis is an infection located in bone and a notoriously difficult disease to manage, requiring frequent and heavy doses of systemically administered antibiotics. Targeting antibiotics to the bone after systemic administration may provide both grea
