92598-99-7

Basic information

• Product Name: (2S,3R)-2-Ethyl-3-hydroxymethyl-4-(3-methyl-3H-imidazol-4-yl)-butyric acid 4-tert-butyl-benzyl ester
• Synonyms: (2S,3R)-2-Ethyl-3-hydroxymethyl-4-(3-methyl-3H-imidazol-4-yl)-butyric acid 4-tert-butyl-benzyl ester
• CAS NO: 92598-99-7
• Molecular Weight: 372.508
• Mol File: 92598-99-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,3R)-2-Ethyl-3-hydroxymethyl-4-(3-methyl-3H-imidazol-4-yl)-butyric acid 4-tert-butyl-benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R)-2-Ethyl-3-hydroxymethyl-4-(3-methyl-3H-imidazol-4-yl)-butyric acid 4-tert-butyl-benzyl ester(92598-99-7)
• EPA Substance Registry System: (2S,3R)-2-Ethyl-3-hydroxymethyl-4-(3-methyl-3H-imidazol-4-yl)-butyric acid 4-tert-butyl-benzyl ester(92598-99-7)

Safety Data

• Hazardous Substances Data: 92598-99-7(Hazardous Substances Data)

Upstream product

• 92598-79-3 sodium pilocarpate 
• 54-71-7 pilocarpine hydrochloride 

Downstream Products

• 92-13-7 pilocarpine 

Relevant articles and documents

Pilocarpic acid esters as novel sequentially labile pilocarpine prodrugs for improved ocular delivery

Pilocarpic acid esters are shown to be potentially useful prodrugs of pilocarpine with the aim of improving its ocular delivery characteristics. The diesters are of particular interest since they combine an enhanced bioavailability and greatly prolonged duration of activity with a high stability in eye-drop formulation. The proprodrug or sequential cascade concept utilized in the design of these derivatives, involving and enzymatic cleavage mechanisms prior to the occurrence of a chemical (nonenzymatic) reaction, may also be of more general interest in prodrug design.