926315-12-0

Basic information

• Product Name: 1-Oxaspiro[2.5]octane-2-methanol, 7-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-methylene-, 2-benzoate, (2R,3S,5S)-
• CAS NO: 926315-12-0
• Molecular Formula: C22H32O4Si
• Molecular Weight: 388.579
• Mol File: 926315-12-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-Oxaspiro[2.5]octane-2-methanol, 7-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-methylene-, 2-benzoate, (2R,3S,5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Oxaspiro[2.5]octane-2-methanol, 7-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-methylene-, 2-benzoate, (2R,3S,5S)-(926315-12-0)
• EPA Substance Registry System: 1-Oxaspiro[2.5]octane-2-methanol, 7-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-methylene-, 2-benzoate, (2R,3S,5S)-(926315-12-0)

Safety Data

• Hazardous Substances Data: 926315-12-0(Hazardous Substances Data)

Upstream product

• 50-14-6 vitamin D₂ 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 96685-53-9 (2Z)-2-<(5S)-5-(tert-butyldimethylsilyloxy)-2-methylene-cyclohexylidene>-ethanol 
• 98-88-4 benzoyl chloride 
• 138381-65-4 (2R,3S,7S)-[7-((t-butyldimethyl)silanyloxy)-4-methylene-1-oxa-spiro[2.5]oct-2-yl]-methanol 

Downstream Products

• 199798-84-0 1-alpha-fluoro-25-hydroxy-16,23E-diene-26,27-bishomo-20-epi-cholecalciferol 
• 926315-15-3 benzoic acid 2-[(3S,5R)-5-(tert-butyl-dimethyl-silanyloxy)-3-fluoro-2-methylene-cyclohex-(Z)-ylidene]-ethyl ester 
• 926315-14-2 benzoic acid (2R,3S,5S,7R)-[7-(t-butyldimethyl)silanyloxy-5-fluoro-4-methylene-1-oxa-spiro[2.5]oct-2-yl] methyl ester 
• 123836-61-3 <3S-(1Z,3β,5α)>-<3-Fluoro-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylenecyclohexylidene>ethanol 
• 123836-62-4 <1R-(1β,3Z,5α)>-<<3-(2-Chloroethylidene)-5-fluoro-4-methylenecyclohexyl>oxy>(1,1-dimethylethyl)dimethylsilane 
• 123836-63-5 <3S-(1Z,3α,5β)>-<2-<3-Fluoro-5-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-methylenecyclohexylidene>ethyl>diphenylphosphine Oxide 
• 1014718-14-9 C₃₇H₅₉⁽²⁾H₆FO₂Si₂ 
• 1014718-19-4 1α-tert-butyl-dimethyl-silanyloxy-3β-fluoro-25-trimethylsilanyloxy-16-ene-20-cyclopropyl-26,27-hexadeutero-cholecalciferol 
• 199798-99-7 C₃₈H₆₅FO₂Si₂ 
• 1014717-86-2 C₄₅H₆₉⁽²⁾H₆F₇O₃Si₃ 
• 1014717-93-1 C₄₅H₆₉⁽²⁾H₆F₇O₃Si₃ 
• 1014717-90-8 C₄₅H₇₁⁽²⁾H₆F₇O₃Si₃ 
• 1014718-06-9 C₄₅H₇₁⁽²⁾H₆F₇O₃Si₃ 
• 1014718-01-4 C₄₅H₇₁⁽²⁾H₆F₇O₃Si₃ 

Relevant articles and documents

SYNTHESIS OF 1α-FLUORO-25-HYDROXY-16-23E-DIENE-26,27-BISHOMO-20-EPI-CHOLECALCIFEROL

The invention provides a method of producing 20-methyl vitamin D3 compounds of formula (I). The method includes hydroxylation, carbonyl reduction, fluoride substitution, epoxide deoxygenation, and Wittig-type couplings.

NOVEL METHOD

There is provided a method of prevention of adhesions, eg surgical adhesions, which comprises using a vitamin D compound.

NOVEL METHOD

The invention provides for the use of Vitamin D compounds such as 1-alpha-fluoro-25- hydroxy-16,23E-diene-26,27-bishomo-20-epi-cholecalciferol, in the prevention or treatment of prostate cancer.