92664-38-5Relevant articles and documents
Method for catalytically synthesizing acrylamide compound by MOFs-derived zirconium-based ternary oxide solid acid
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Paragraph 0065-0068, (2021/11/14)
The invention provides a catalytic synthesis of acrylamide compounds with zirconium-based ternary oxide solid acid as a catalyst, and the low-temperature activity is good. In the synthesis process, the acid is small, the reaction conditions are mild and controllable, the byproducts are few, the reaction yield is effectively improved, the purity is high, the quality is good, and the method is suitable for large-scale production.
COVALENT TARGETING OF E3 LIGASES
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Paragraph 0591; 0622; 0741, (2020/05/19)
Disclosed herein, inter alia, are compositions and methods for targeting E3 ligases. In an aspect is a targeted protein degrader including 1) a targeted protein binder and 2) an E3 Ubiquitin ligase binder, wherein the E3 Ubiquitin ligase is human RNF4 or human RNF114. In an aspect is provided a pharmaceutical composition including a compound as described herein, including embodiments, and a pharmaceutically acceptable excipient.
Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells
Berdan, Charles A.,Ho, Raymond,Lehtola, Haley S.,To, Milton,Hu, Xirui,Huffman, Tucker R.,Petri, Yana,Altobelli, Chad R.,Demeulenaere, Sasha G.,Olzmann, James A.,Maimone, Thomas J.,Nomura, Daniel K.
, p. 1027 - 22,1035 (2019/07/17)
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