928853-01-4

Basic information

• Product Name: Pentanedioic acid, 2-bromo-4-[5-(phenylmethyl)-2H-tetrazol-2-yl]-, 1,5-dimethyl ester
• CAS NO: 928853-01-4
• Molecular Formula: C15H17BrN4O4
• Molecular Weight: 397.228
• Mol File: 928853-01-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Pentanedioic acid, 2-bromo-4-[5-(phenylmethyl)-2H-tetrazol-2-yl]-, 1,5-dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanedioic acid, 2-bromo-4-[5-(phenylmethyl)-2H-tetrazol-2-yl]-, 1,5-dimethyl ester(928853-01-4)
• EPA Substance Registry System: Pentanedioic acid, 2-bromo-4-[5-(phenylmethyl)-2H-tetrazol-2-yl]-, 1,5-dimethyl ester(928853-01-4)

Safety Data

• Hazardous Substances Data: 928853-01-4(Hazardous Substances Data)

Upstream product

• 31358-13-1 dimethyl 2,4-dibromopentanedioate 
• 18489-25-3 5-benzyl-2H-tetrazole 

Downstream Products

• 928853-07-0 4-(5-benzyl-tetrazol-2-yl)-5-oxo-pyrrolidine-2-carboxylic acid methyl ester 
• 928853-04-7 2-azido-4-(5-benzyl-tetrazol-2-yl)-pentanedioic acid dimethyl ester 

Relevant articles and documents

Synthesis of new tetrazole and triazole substituted pyroglutamic acid and proline derivatives

Racemic 4-(substituted-1H-1,2,3-triazol-1-yl), 4-aryl and 4-(arylmethyl)tetrazolyl-pyroglutamic and proline derivatives were synthesized from dimethyl-2,4-dibromoglutaryle 1 in good yield using mild reaction conditions. The key step for the preparation of the triazole substituted molecule was the 1,3-dipolar cycloaddition of an acetylenic compound with an azido derivative. The tetrazole derivatives were prepared by the selective N2-alkylation of 5-substituted tetrazoles with 1.