93-00-5

Basic information

• Product Name: 6-Amino-2-naphthalenesulfonic acid
• Synonyms: 6-AMINO-2-NAPHTHALENESULFONIC ACID;6-AMINO-2-NAPHTHALENESULFONIC ACID MONOHYDRATE;6-AMINO NAPHTHALENE-2-SULFONIC ACID;6-Aminonaphthalene-2-sulphonic acid;2-NAPHTHYLAMINE-6-SULFONIC ACID;2-NAPHTHYLAMINE-6-SULFONIC ACID MONOHYDRATE;BRONNER ACID;BRONNER'S ACID
• CAS NO: 93-00-5
• Molecular Formula: C₁₀H₉NO₃S
• Molecular Weight: 223.25
• EINECS: 202-208-9
• Product Categories: Intermediates of Dyes and Pigments;Dye
• Mol File: 93-00-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 500oC
• Appearance: /
• Density: 1.3588 (rough estimate)
• Vapor Pressure: 0Pa at 25℃
• Refractive Index: 1.6500 (estimate)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: -0.08±0.40(Predicted)
• Water Solubility: 0.12g/L(20 oC)
• CAS DataBase Reference: 6-Amino-2-naphthalenesulfonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Amino-2-naphthalenesulfonic acid(93-00-5)
• EPA Substance Registry System: 6-Amino-2-naphthalenesulfonic acid(93-00-5)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 93-00-5(Hazardous Substances Data)

Usage

Uses

6-Amino-2-naphthalenesulfonic Acid is used in the synthesis of diaryl urea derivatives bearing sulfonamide moiety with an in vitro antitumor activity.

Flammability and Explosibility

Notclassified

Purification Methods

Crystallise the acid from a large volume of hot water. The diethylamine salt has m 190.5-192o (from EtOH/isoBuOH), and the S-benzylisothiuronium salt has m 330o (from nBuOH). [Beilstein 14 H 760, 14 II 463, 14 III 2249, 14 IV 2804.]

InChI:InChI=1/C10H9NO3S/c11-9-3-1-8-6-10(15(12,13)14)4-2-7(8)5-9/h1-6H,11H2,(H,12,13,14)/p-1

Upstream product

• 117-62-4 2-amino-1,5-naphthalenedisulfonic acid 
• 93-01-6 2-naphthol-6-sulfonic acid 
• 15509-36-1 3-hydroxy-7-sulfo-[2]naphthoic acid 
• 135-19-3 β-naphthol 
• 81-16-3 2-aminonaphthalenesulfonic acid 
• 7664-93-9 sulfuric acid 
• 91-59-8 naphthalen-2-ylamine 
• 7446-11-9 sulfur trioxide 
• 7664-41-7 ammonia 
• 81-05-0 6-aminonaphthalene-1-sulfonic acid 
• 86-60-2 7-aminonaphthalene-1-sulfonic acid 
• 74631-01-9 [2]naphthylamine; sulfate 

Downstream Products

• 7724-15-4 6-p-toluidinonaphthalene-2-sulfonic acid 
• 109594-35-6 2-(4-amino-phenyl)-naphtho[2,1-d]thiazole-7-sulfonic acid 
• 20096-53-1 2-anilinonaphthalene-6-sulfonic acid 
• 855284-29-6 benzo[f]quinoline-8-sulfonic acid 
• 6481-89-6 6-amino-5-phenylazo-naphthalene-2-sulfonic acid 
• 6838-02-4 2-amino-naphthalene-1,6-disulfonic acid 
• 86-65-7 2-aminonaphthalene-6,8-disulfonate 
• 57189-62-5 6-Brom-2-naphthalinsulfonsaeure 
• 102878-14-8 6-chloro-2-naphthalenesulphonic acid 
• 93-01-6 2-naphthol-6-sulfonic acid 
• 60201-22-1 (6-methoxy-2-naphthyl)methanol 

Relevant articles and documents

Triphendioxazine dyestuffs

The novel triphendioxazine dyestuffs of the formula STR1 in which the substituents R, R', T1, T2, X, Y and n have the meanings given in the description are highly suitable for the dyeing and printing of cellulose-containing or amido-containing material.

Reactive dye having both monochlorotriazinyl and vinylsulfone type reactive groups

A novel reactive monoazo dye, capable of giving cellulose fiber materials a deep orange to scarlet color and superior in build-up and chlorine fastness properties, represented by a free acid of the formula, STR1 wherein R1 is hydrogen, methyl or ethyl; R2 is an alkyl having 1 to 4 carbons that is either unsubstituted or substituted with hydroxy, cyano, alkoxy, halogen, carboxy, alkoxycarbonyl or sulfonic acid; Z is hydrogen or sulfonic acid; A is phenylene and is either unsubstituted or substituted with 1 or 2 substituents selected from the group consisting of methyl, ethyl, methoxy, ethoxy, chlorine, bromine and sulfonic acid, or natphthylene that is either unsubstituted or substituted with sulfonic acid; X is --SO2 CH=CH2 or --SO2 CH2 CH2 Y in which Y is a group that is splittable by alkalis; and m is an integer of 1 to 3.

Solid phase acylation of aminosulfonic acids

This invention is directed to the acylation of aminosulfonic acids in the solid phase. Two discrete, sequential chemical reactions occur, i.e. (1) the neutralization of the aminosulfonic acid, and (2) the subsequent amine acylation, to produce an improved neutralized acyl-aminosulfonic acid at a reduced cost. Aminosulfonic acids having the general formula HO3 S-A-NH2 are acylated to neutralized acyl-aminosulfonic acids having the general formula RCONH-A-SO3 M, where A is an unsubstituted or substituted aliphatic, aromatic or heteroaromatic group and M is a neutralizing agent moiety. The yield is virtually quantitative.