93-82-3Relevant articles and documents
Synthetic method of coconut diethanol amide
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Paragraph 0019; 0020; 0022; 0024; 0025, (2018/01/13)
The invention particularly relates to a synthetic method of coconut diethanol amide. The synthetic method comprises the following steps that 1, raw materials fatty acid and diethanol amine (DEA) are pretreated and purified; 2, under N2 airflow protection, and the fatty acid and the diethanol amine (DEA) perform amidate and ammonolysis reaction; 3, finally adsorption treatment is performed by using activated carbon, and filtration is performed to obtain the coconut diethanol amide. The 1: 1 coconut diethanol amide prepared by adopting the method has the advantages of being high in purity, light in color and luster, light in smell, low in amine value and the like.
IMPROVED PROCESS FOR ALAKNOLAMIDE SYNTHESIS
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Page/Page column 25, (2016/03/22)
The present invention is directed to a process of making alkanolamides wherein the "aging" time is reduced and the diethanol amide to ester ratio in the finished product is increased. Further provided is an additive composition comprising an alkanolamide which contains a reduced amount of DEA and BHEP.
Low molecular weight PEI-based biodegradable lipopolymers as gene delivery vectors
Xun, Miao-Miao,Zhang, Xue-Chao,Zhang, Ji,Jiang, Qian-Qian,Yi, Wen-Jing,Zhu, Wen,Yu, Xiao-Qi
, p. 1242 - 1250 (2013/03/29)
Non-viral gene vectors play an important role in the development of gene therapy. In this report, different hydrophobic chains were introduced into low molecular weight (LMW) PEI-based biodegradable oligomers to form a series of lipopolymers (LPs), and their structure-activity relationships were studied. Results revealed that the nine polymers can condense plasmid DNA well to form nanoparticles with appropriate sizes (120-250 nm) and positive zeta-potentials (+25-40 V). In vitro experiments were carried out and it was found that LP2 showed much higher transfection efficiency both in the presence and in the absence of serum under the polymer/DNA weight ratio of 0.8 in A549 cells.