930-83-6

Basic information

• Product Name: 4,5-Dimethylisoxazol-3(2H)-one
• Synonyms: 4,5-Dimethylisoxazol-3(2H)-one;4,5-Dimethyl-isoxazol-3-ol
• CAS NO: 930-83-6
• Molecular Formula: C₅H₇NO₂
• Molecular Weight: 113.11
• Mol File: 930-83-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 238°C at 760 mmHg
• Flash Point: 97.7°C
• Appearance: /
• Density: 1.113g/cm³
• Vapor Pressure: 0.0283mmHg at 25°C
• Refractive Index: 1.462
• CAS DataBase Reference: 4,5-Dimethylisoxazol-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-Dimethylisoxazol-3(2H)-one(930-83-6)
• EPA Substance Registry System: 4,5-Dimethylisoxazol-3(2H)-one(930-83-6)

Safety Data

• Hazardous Substances Data: 930-83-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H7NO2/c1-3-4(2)8-6-5(3)7/h1-2H3,(H,6,7)

Upstream product

• 75989-10-5 4,5-dimethyl-3-(phenylsulphonyloxy)isoxazole 
• 609-14-3 2-acetylpropanoic acid ethyl ester 

Downstream Products

• 166180-70-7 (3-ethoxy-4-methylisoxazol-5-yl)carboxylic acid 
• 127020-41-1 (RS)-ethyl 2-amino-3-(3-ethoxy-5-methylisoxazol-4-yl)propionate hydrochloride 
• 127020-42-2 (RS)-2-amino-3-(3-ethoxy-5-methylisoxazol-4-yl)propionic acid hydrochloride 
• 127020-33-1 ethyl 2-acetamido-2-ethoxycarbonyl-3-(2-ethyl-5-methyl-3-oxoisoxazolin-4-yl)propionate 
• 127020-34-2 ethyl 2-acetamido-2-ethoxycarbonyl-3-(2-ethyl-3-hydroxy-5-methylisoxazol-4-yl)propionate 
• 75989-10-5 4,5-dimethyl-3-(phenylsulphonyloxy)isoxazole 
• 75989-11-6 4,5-dimethyl-2-(phenylsulphonyl)isoxazol-3-one 
• 93001-93-5 3-benzoyloxy-4,5-dimethyl-isoxazole 
• 91569-60-7 2-benzoyl-4,5-dimethyl-isoxazol-3-one 

Relevant articles and documents

Indole-2,3-dione-3-oxime derivatives for therapeutic use

The present invention relates to the use of indole-2,3-dione-3-oxime derivatives in a method of combating diseases and disorders associated with or mediated by the release of excitatory amino acids.

Synthesis of 3-Hydroxyisoxazoles from β-Ketoesters and Hydroxylamine

An efficient synthesis of 3-hydroxyisoxazoles from β-ketoesters and hydroxylamine was investigated.The reaction of the sodium salts of β-ketoesters and hydroxylamine at a low temperature, followed by quenching with an excess of conc.HCl under heating gave predominantly 3-hydroxyisoxazoles involving 4-sulfenylated 3-hydroxyisoxazoles.Starting from the prepared 4-(2,4-dichlorobenzyl)-3-hydroxy-5-methylisoxazole, a potential herbicidal compound, 4-(2,4-dichlorobenzoyl)-3-hydroxy-5-methylisoxazole, was also synthesized in five steps.

Isoxazole amino-acids as glutamic acid agonists. Synthesis of some analogues and homologues of ibotenic acid.

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