931101-84-7

Basic information

• Product Name: Troplasminogen alfa
• Synonyms: troplasminogen alfa;Plasminogen
• CAS NO: 931101-84-7
• Molecular Weight: 0
• Mol File: 931101-84-7.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Troplasminogen alfa(CAS DataBase Reference)
• NIST Chemistry Reference: Troplasminogen alfa(931101-84-7)
• EPA Substance Registry System: Troplasminogen alfa(931101-84-7)

Safety Data

• Hazardous Substances Data: 931101-84-7(Hazardous Substances Data)

Usage

Description

Troplasminogen alfa is a recombinant form of human plasminogen, a profibrinolysin from human serum. It is a single chain glycoprotein that exists in various isoelectric forms, which can be separated by isoelectric focusing (IEF). The lyophilizate is stabilized with bovine serum albumin (BSA). Troplasminogen alfa serves as a substrate for tissue plasminogen activator (t-PA) in the t-PA test and acts as a reference substance for t-PA therapy.

Uses

Used in Pharmaceutical Industry:
Troplasminogen alfa is used as a substrate for tissue plasminogen activator (t-PA) in the t-PA test, which is essential for determining the activity of plasminogen activators. This helps in the diagnosis and treatment of various conditions related to blood clotting and fibrinolysis.
Used in Research and Development:
Troplasminogen alfa is used as a reference substance for t-PA therapy, aiding in the development and optimization of fibrinolytic drugs and therapies. It provides a standard for comparison and ensures the effectiveness and safety of these treatments.
Used in Quality Control:
Troplasminogen alfa is used as an in-process control in the production of tissue plasminogen activator (t-PA), ensuring the quality and consistency of the final product. This is crucial for maintaining the efficacy and safety of t-PA as a therapeutic agent.