93118-03-7

Basic information

• Product Name: 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE
• Synonyms: 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE;TIMTEC-BB SBB003469;2-Chloro-3-(trifluoromethyl)benzaldehyde 98%;2-Chloro-3-(trifluoromethyl)benzaldehyde98%;2-Fluoro-4-hydroxybenzonitrile;2-Choro-3-(trifluoroMethyl)benzaldehyde
• CAS NO: 93118-03-7
• Molecular Formula: C₈H₄ClF₃O
• Molecular Weight: 208.56
• Product Categories: Benzaldehyde;Aldehydes;C8;Carbonyl Compounds
• Mol File: 93118-03-7.mol
• Article Data: 8

Chemical Properties

• Melting Point: 37-43 °C(lit.)
• Boiling Point: 216.6 °C at 760 mmHg
• Flash Point: >230 °F
• Appearance: White to off-white/Crystals or Powder
• Density: 1.423 g/cm³
• Vapor Pressure: 0.139mmHg at 25°C
• Refractive Index: 1.496
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive: Air Sensitive
• BRN: 3543607
• CAS DataBase Reference: 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE(93118-03-7)
• EPA Substance Registry System: 2-CHLORO-3-(TRIFLUOROMETHYL)BENZALDEHYDE(93118-03-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 93118-03-7(Hazardous Substances Data)

Usage

General Description

4-Chloro-3-(trifluoromethyl)benzaldehyde is a substituted benzaldehyde.

InChI:InChI=1/C8H4ClF3O/c9-7-5(4-13)2-1-3-6(7)8(10,11)12/h1-4H

Upstream product

• 88-16-4 1-chloro-2-(trifluoromethyl)benzene 
• 60-29-7 diethyl ether 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 123753-84-4 4-<2-chloro-3-(trifluoromethyl)phenyl>-1,4-dihydro-2-(1H-imidazol-1-ylmethyl)-6-methylpyridine-3,5-dicarboxylic acid 3-ethyl 5-methyl diester 
• 1186033-49-7 C₁₀H₉F₃OS 
• 1193686-59-7 C₃₅H₃₅ClF₃NO₃ 
• 609849-26-5 C₃₅H₃₁ClF₃NO₃ 
• 609772-21-6 C₃₅H₃₁ClF₃NO₃ 
• 1246376-25-9 2-(2-chloro-3-(trifluoromethyl)phenyl)-6-methyl-2H-pyran-4(3H)-one 
• 1422961-61-2 3-pyridylmethyl 7-(2-chloro-3-trifluoromethylphenyl)-5-methyl-2,3,4,7-tetrahydro-thieno[3,2-b]pyridine-6-carboxylate-1,1-dioxide 
• 1422961-56-5 3-pyridylmethyl 2-methyl-4-(2-chloro-3-trifluoromethylphenyl)-5-oxo-4,5,6,7-tetra-hydro-1Hcyclopenta[b]pyridine-3-carboxylate 
• 1422961-66-7 3-pyridylmethyl 2-methyl-4-(2-chloro-3-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 
• 1422961-71-4 3-pyridylmethyl 2,6,6-trimethyl-4-(2-chloro-3-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 
• 1422961-75-8 3-pyridylmethyl 2,7,7-trimethyl-4-(2-chloro-3-trifluoromethylphenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate 

Relevant articles and documents

BICYCLONONENE DERIVATIVES AS RENIN INHIBITORS

The invention relates to novel bicyclononene derivatives of Formula (I); and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.

Process for 1,4-dihydropyridine compounds

The invention relates to a process for producing new compounds of formula I: STR1 and isomers thereof, as well as acid addition salts thereof, in which the symbols have the meanings set forth in the specification.

Dihydropyridines

Dihydropyridine anti-ischaemic agents of the formula: STR1 and their salts where R is aryl or heteroaryl, R1 and R2 are each C1 -C4 alkyl or 2-methoxyethyl, Y is --(CH2)n -- where n is 2, 3, or 4 and is optionally substituted by 1 or 2 CH3 groups, and R3 is an optionally substituted 5- or 6-membered heterocyclic group attached to the adjacent N atom by a C atom, said group R3 being optionally fused to a further heterocyclic group or to a benzene ring.