93247-78-0

Basic information

• Product Name: Methyl 1H-indole-7-carboxylate
• Synonyms: RARECHEM AL BF 0640;METHYL INDOLE-7-CARBOXYLATE;METHYL 1H-INDOLE-7-CARBOXYLATE;INDOLE-7-CARBOXYLIC ACID METHYL ESTER;7-INDOLECARBOXYLIC ACID METHYL ESTER;1H-INDOLE-7-CARBOXYLIC ACID METHYL ESTER;Methyl 1H-indole-7-c;7-(Methoxycarbonyl)-1H-indole
• CAS NO: 93247-78-0
• Molecular Formula: C₁₀H₉NO₂
• Molecular Weight: 175.18
• EINECS: 1308068-626-2
• Product Categories: blocks;Carboxes;IndolesOxindoles;Indoles and derivatives;Indole
• Mol File: 93247-78-0.mol
• Article Data: 14

Chemical Properties

• Melting Point: 47-48°C
• Boiling Point: 331.7 °C at 760 mmHg
• Flash Point: 154.4 °C
• Appearance: /Solid
• Density: 1.253 g/cm³
• Vapor Pressure: 0.000153mmHg at 25°C
• Refractive Index: 1.639
• Storage Temp.: Store below +30°C.
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 15.42±0.30(Predicted)
• CAS DataBase Reference: Methyl 1H-indole-7-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 1H-indole-7-carboxylate(93247-78-0)
• EPA Substance Registry System: Methyl 1H-indole-7-carboxylate(93247-78-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-37/39
• WGK Germany: WGK 3 highly water endangering
• HazardClass: IRRITANT
• Hazardous Substances Data: 93247-78-0(Hazardous Substances Data)

Usage

Uses

Methyl Indole-7-carboxylate is useful for the preparation of inhibitors of CD38, which are useful in the treatment of cancer.

InChI:InChI=1/C10H9NO2/c1-13-10(12)8-4-2-3-7-5-6-11-9(7)8/h2-6,11H,1H3

Upstream product

• 5471-82-9 methyl 3-methyl-2-nitrobenzoate 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 67-56-1 methanol 
• 1670-83-3 1H-Indole-7-carboxylic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 104670-71-5 methyl 3-bromo-2-nitrobenzoate 
• 5437-38-7 3-methyl-2-nitrobenzoic acid 
• 132874-06-7 methyl 3-(bromomethyl)-2-nitrobenzoate 
• 51417-51-7 7-bromo-1H-indole 
• 201230-82-2 carbon monoxide 
• 126759-37-3 methyl 3-ethenyl-2-nitrobenzoate 
• 79-22-1 methyl chloroformate 
• 126759-45-3 <(3-methoxycarbonyl-2-nitrophenyl)methyl>-1,3-dioxane 
• 68109-89-7 methyl 3-[2-(E)-(dimethylamino)ethenyl]-2-nitro-benzoate 

Downstream Products

• 1027073-83-1 1-[3-(4-Benzhydryl-piperazin-1-yl)-propyl]-3-imidazol-1-ylmethyl-1H-indole-7-carboxylic acid methyl ester 
• 312915-01-8 methyl 3-dimethylaminomethylindole-7-carboxylate 
• 1074-87-9 indole-7-methanol 
• 729614-30-6 methyl 5-benzyl-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylate 
• 1027787-38-7 methyl 1-benzyl-3-iodo-1H-indole-7-carboxylate 
• 917562-23-3 1-(tert-butyl) 7-methyl 1H-indole-1,7-dicarboxylate 
• 955039-54-0 methyl 4-{(1S)-1-[({1-[3-(trifluoromethyl)benzyl]-1H-indol-7-yl}carbonyl)amino]ethyl}benzoate 
• 1238214-74-8 1-[3-(trifluoromethyl)benzyl]-1H-indole-7-carboxylic acid 
• 955039-58-4 1-(3-chlorophenyl)-1H-indole-7-carboxylic acid 

Relevant articles and documents

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