93293-21-1 Usage
General Description
3-(4-Chloro-benzyl)-pyridine is a chemical compound with the molecular formula C12H10ClN. It is a pyridine derivative with a 4-chlorobenzyl group attached to the third position of the pyridine ring. 3-(4-CHLORO-BENZYL)-PYRIDINE is commonly used in the synthesis of various pharmaceuticals and agrochemicals. It has been identified as a potential intermediate in the preparation of antihypertensive agents, antitumor agents, and insecticides. The 4-chlorobenzyl group in 3-(4-Chloro-benzyl)-pyridine is considered to be important for its biological activity and has been utilized in the development of new drug candidates. Additionally, this chemical is also used as a building block in organic synthesis for the preparation of various functionalized pyridine derivatives.
Check Digit Verification of cas no
The CAS Registry Mumber 93293-21-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,2,9 and 3 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 93293-21:
(7*9)+(6*3)+(5*2)+(4*9)+(3*3)+(2*2)+(1*1)=141
141 % 10 = 1
So 93293-21-1 is a valid CAS Registry Number.
93293-21-1Relevant articles and documents
Transforming Benzylic Amines into Diarylmethanes: Cross-Couplings of Benzylic Pyridinium Salts via C-N Bond Activation
Liao, Jennie,Guan, Weiye,Boscoe, Brian P.,Tucker, Joseph W.,Tomlin, John W.,Garnsey, Michelle R.,Watson, Mary P.
, p. 3030 - 3033 (2018/05/28)
A nickel-catalyzed cross-coupling of benzylic pyridinium salts with arylboronic acids was developed. Coupled with chemoselective pyridinium formation, this method allows benzyl primary amines to be efficiently converted to di(hetero)arylmethanes. Excellent heteroaryl and functional group tolerance is observed, and a one-pot procedure enables benzylic amines to be converted to diarylmethanes directly.
REGIOSELECTIVE ALKYL GROUP INTRODUCTION AT THE 3-POSITION OF PYRIDINE VIA 1,4-BIS(TRIMETHYLSILYL)-1,4-DIHYDROPYRIDINE
Tsuge, Otohiko,Kanemasa, Shuji,Naritomi, Toshio,Tanaka, Junji
, p. 1255 - 1258 (2007/10/02)
The reaction of 1,4-bis(trimethylsilyl)-1,4-dihydropyridine with aldehydes and ketones in the presence of tetrabutylammonium fluoride offers a convenient method for the preparation of 3-alkylpyridines.
