934180-48-0

Basic information

• Product Name: 4-Chloro-2-Methoxy-3-nitropyridine
• Synonyms: 4-Chloro-2-Methoxy-3-nitropyridine
• CAS NO: 934180-48-0
• Molecular Formula: C6H5ClN2O3
• Molecular Weight: 188.5685
• Mol File: 934180-48-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 276.0±35.0 °C(Predicted)
• Appearance: /
• Density: 1.445±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 1.04±0.10(Predicted)
• CAS DataBase Reference: 4-Chloro-2-Methoxy-3-nitropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-2-Methoxy-3-nitropyridine(934180-48-0)
• EPA Substance Registry System: 4-Chloro-2-Methoxy-3-nitropyridine(934180-48-0)

Safety Data

• Hazardous Substances Data: 934180-48-0(Hazardous Substances Data)

Usage

General Description

4-Chloro-2-Methoxy-3-nitropyridine is a chemical compound with the molecular formula C6H5ClN2O3. It is a yellow crystalline solid that is widely used in the pharmaceutical and agricultural industries as an intermediate in the synthesis of various organic compounds. This chemical is known for its ability to act as a building block in the production of agrochemicals and pharmaceuticals, as well as in the development of advanced materials. It is known for its versatility as a key component in the synthesis of various drugs and pesticides, and its unique properties make it a valuable tool in the development of new chemical compounds. Additionally, its nitro and methoxy functional groups make it a valuable tool for creating novel molecules with potential applications in various fields.

Upstream product

• 165547-79-5 4-chloro-3-nitropyridin-2(1H)-one 
• 74-88-4 methyl iodide 
• 165547-79-5 2-hydroxy-3-nitro-4-chloropyridine 

Downstream Products

• 1210835-26-9 C₁₃H₈ClN₃O₄ 
• 934180-49-1 4-chloro-2-methoxypyridin-3-amine 

Relevant articles and documents

C5A RECEPTOR MODULATORS

The present invention relates to derivatives of formula (I) wherein ring A, X, Y, Z, R1, R2, R3 and R4 are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as C5a receptor modulators.

9-AZABICYCLO [3 . 3 . 1] NONANE DERIVATIVES AS MONOAMINE REUPTAKE INHIBITORS

The present invention relates to a 9-azabicyclo[3.3.1]nonane derivative of formula (I), wherein R1 is H or C1-5alkyl; X is O or NR2, wherein R2 is H, C1-5alkyl or C2-5acyl and Ar is C6-10aryl or a 5-10 membered heteroaryl ring system, both being optionally substituted with one to three of R3-R5 independently selected from halogen, C1-5alkyl, C1-5alkoxy, C3-6cycloalkyl, C2-5alkenyl, C2-5alkynyl, CN, NO2, hydroxy, phenyl, phenoxy and phenylC1-2alkoxy, wherein said C1-5alkyl and C1-5alkoxy are optionally substituted with one to three halogens and wherein said phenyl, phenoxy and phenylC1-2alkoxy are optionally substituted with one to three substituents independently selected from halogen and methyl or two of R3-R5 at adjacent positions together form a methylenedioxy or propylene unit, with the proviso that the compounds exo-9-methyl-3-phenoxy-9-azabicyclo[3.3.1]nonane and N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-1H indazole-5-amine are excluded, or a pharmaceutically acceptable salt or solvate thereof. The invention also relates to pharmaceutical compositions comprising said 9-azabicyclo[3.3.1]nonane derivatives and to their use in therapy.