934183-50-3

Basic information

• Product Name: FMOC-MET-OH-15N
• Synonyms: N-(9-FLUORENYLMETHOXYCARBONYL)-L-METHIONINE-15N;L-METHIONINE-15N, N-FMOC DERIVATIVE;FMOC-MET-OH-15N;L-Methionine-15N, N-Fmoc, N-(9-Fluorenylmethoxycarbonyl)-L-methionine-15N;L-Methionine-15N，N-Fmoc;FMoc-Met-OH-15N
• CAS NO: 934183-50-3
• Molecular Formula: C20H21NO4S
• Molecular Weight: 372.46
• Mol File: 934183-50-3.mol
• Article Data: 0

Chemical Properties

• Melting Point: 121-123 °C(lit.)
• Appearance: /
• CAS DataBase Reference: FMOC-MET-OH-15N(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-MET-OH-15N(934183-50-3)
• EPA Substance Registry System: FMOC-MET-OH-15N(934183-50-3)

Safety Data

• Hazard Codes: N
• Statements: 50
• Safety Statements: 60-61
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 934183-50-3(Hazardous Substances Data)

Usage

Description

Fmoc-Met-OH-15N is a chemical compound that features the amino acid methionine enriched with the stable nitrogen isotope 15N. Fmoc-Met-OH-15N is distinguished by the presence of the Fmoc (9-fluorenylmethoxycarbonyl) group, which acts as a protective agent for the amino acid, facilitating selective deprotection and the efficient synthesis of peptides. The incorporation of 15N labeling enables researchers to trace the metabolic pathway of methionine within biological systems and to probe the structure and dynamics of proteins in complex biological samples. Fmoc-Met-OH-15N serves as an indispensable tool for scientists delving into the intricate roles that methionine plays in a variety of biological processes.

Uses

Used in Protein Research:
Fmoc-Met-OH-15N is utilized as a research tool for studying protein structure and dynamics. The 15N labeling allows for detailed investigation of protein behavior in complex biological samples, providing insights into the molecular mechanisms at play.
Used in Mass Spectrometry:
In the field of mass spectrometry, Fmoc-Met-OH-15N is employed to enhance the detection and analysis of peptides and proteins. The 15N labeling aids in the differentiation of isotopologues, improving the accuracy and precision of mass spectrometry-based protein identification and quantification.
Used in Nuclear Magnetic Resonance (NMR) Spectroscopy:
Fmoc-Met-OH-15N serves as a vital component in NMR spectroscopy for the study of protein structure. The stable isotope labeling with 15N enriches the NMR signals, enabling researchers to more effectively analyze the three-dimensional structure and conformational changes of proteins.
Used in Metabolic Studies:
Fmoc-Met-OH-15N is applied as a tracer in metabolic studies to track the fate of methionine in biological systems. This allows researchers to monitor metabolic pathways and understand the role of methionine in various physiological and pathological processes.
Used in Peptide Synthesis:
In the synthesis of peptides, Fmoc-Met-OH-15N is used as a building block. The Fmoc group provides a means for selective protection and deprotection of the amino acid, streamlining the peptide synthesis process and enhancing the yield of desired peptide sequences.
Overall, Fmoc-Met-OH-15N is a multifaceted compound with applications across various scientific disciplines, particularly in the study and manipulation of proteins and peptides in biological research.