934279-60-4

Basic information

• Product Name: 3-PYRIDINECARBOXALDEHYDE, 2-CHLORO-5-(TRIFLUOROMETHYL)-
• Synonyms: 2-CHLORO-5-(TRIFLUOROMETHYL)PYRIDINE-3-CARBALDEHYDE;3-PYRIDINECARBOXALDEHYDE, 2-CHLORO-5-(TRIFLUOROMETHYL)-;2-Chloro-3-formyl-5-trifluoromethylpyridine;2-Chloro-5-(trifluoroMethyl)pyridin-3-carbaldehyde;2-chloro-5-(trifluoroMethyl)nicotinaldehyde;2-Chloro-5-(trifluoromethyl)pyridine-3-carboxaldehyde, 2-Chloro-3-formyl-5-(trifluoromethyl)pyridine
• CAS NO: 934279-60-4
• Molecular Formula: C₇H₃ClF₃NO
• Molecular Weight: 209.554
• Mol File: 934279-60-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 233.821°C at 760 mmHg
• Flash Point: 95.212°C
• Appearance: /
• Density: 1.499g/cm³
• Vapor Pressure: 0.055mmHg at 25°C
• Refractive Index: 1.498
• Storage Temp.: Room temperature.
• PKA: -4.07±0.10(Predicted)
• CAS DataBase Reference: 3-PYRIDINECARBOXALDEHYDE, 2-CHLORO-5-(TRIFLUOROMETHYL)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PYRIDINECARBOXALDEHYDE, 2-CHLORO-5-(TRIFLUOROMETHYL)-(934279-60-4)
• EPA Substance Registry System: 3-PYRIDINECARBOXALDEHYDE, 2-CHLORO-5-(TRIFLUOROMETHYL)-(934279-60-4)

Safety Data

• Hazardous Substances Data: 934279-60-4(Hazardous Substances Data)

Usage

General Description

3-Pyridinecarboxaldehyde, 2-chloro-5-(trifluoromethyl)- is a chemical compound bearing the molecular formula C8H4ClF3NO. It is a yellow liquid that is commonly used in the synthesis of pharmaceuticals and agricultural chemicals. 3-PYRIDINECARBOXALDEHYDE, 2-CHLORO-5-(TRIFLUOROMETHYL)- is an aromatic aldehyde with a pyridine ring and a chloro-trifluoromethyl group attached to it. It can also be utilized as a building block in the production of various biologically active compounds and in the development of new materials. Additionally, it has applications in the field of organic synthesis and chemical research.

InChI:InChI=1/C7H3ClF3NO/c8-6-4(3-13)1-5(2-12-6)7(9,10)11/h1-3H

Upstream product

• 71701-92-3 2-chloro-3-bromo-5-(trifluoromethyl)pyridine 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1026086-96-3 2-chloro-5-(trifluoromethyl)pyridin-3-ylmethane chloride 
• 943551-28-8 (2-chloro-5-(trifluoromethyl)pyridin-3-yl)methanol 

Relevant articles and documents

NOVEL SUBSTITUTED BIARYL COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS

Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.

HETEROCYCLIC DERIVATIVES AS CETP INHIBITORS

The present invention provides a compound of formula (I), said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.

PYRIDINYL AMINE DERIVATIVES AS INHIBITORS OF CHOLESTERYL ESTER TRANSFER PROTEIN (CETP)

The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein the variables are as defined, useful as inhibitors of chlosteryl ester transfer protein.