935759-87-8

Basic information

• Product Name: 4-oxo-N-[(3-{4-[(5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)acetyl]piperazin-1-yl}phenyl)methyl]-3,4-dihydroquinazoline-2-carboxamide
• Synonyms: 4-oxo-N-[(3-{4-[(5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)acetyl]piperazin-1-yl}phenyl)methyl]-3,4-dihydroquinazoline-2-carboxamide
• CAS NO: 935759-87-8
• Molecular Weight: 488.506
• Mol File: 935759-87-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-oxo-N-[(3-{4-[(5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)acetyl]piperazin-1-yl}phenyl)methyl]-3,4-dihydroquinazoline-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-oxo-N-[(3-{4-[(5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)acetyl]piperazin-1-yl}phenyl)methyl]-3,4-dihydroquinazoline-2-carboxamide(935759-87-8)
• EPA Substance Registry System: 4-oxo-N-[(3-{4-[(5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)acetyl]piperazin-1-yl}phenyl)methyl]-3,4-dihydroquinazoline-2-carboxamide(935759-87-8)

Safety Data

• Hazardous Substances Data: 935759-87-8(Hazardous Substances Data)

Upstream product

• 31197-30-5 1-(3-bromophenyl)piperazine 
• 327030-39-7 1,1-dimethylethyl 4-(3-bromophenyl)piperazine-1-carboxylate 
• 807624-20-0 1,1-dimethylethyl 4-(3-cyanophenyl)piperazine-1-carboxylate 
• 889948-55-4 1,1-dimethylethyl 4-[3-(aminomethyl)phenyl]piperazine-1-carboxylate 
• 935760-79-5 1,1-dimethylethyl 4-[3-({[(4-oxo-3,4-dihydroquinazolin-2-yl)carbonyl]amino}methyl)phenyl]piperazine-1-carboxylate 
• 70486-43-0 2‐(5‐oxo‐4,5‐dihydro‐1H‐1,2,4‐triazol‐3‐yl)acetic acid 

Relevant articles and documents

Design, synthesis, and biological activity of novel, potent, and highly selective fused pyrimidine-2-carboxamide-4-one-based matrix metalloproteinase (MMP)-13 zinc-binding inhibitors

Matrix metalloproteinase-13 (MMP-13), a member of the collagenase family of enzymes, has been implicated to play a key role in the pathology of osteoarthritis. Recently, we have reported the discovery of a series of quinazoline-2-carboxamide based non-zin