93614-80-3

Basic information

• Product Name: 2-PROPENAL, 3-(3-METHYLPHENYL)-,(2E)
• Synonyms: 2-PROPENAL, 3-(3-METHYLPHENYL)-,(2E);3-METHYLCINNAMALDEHYDE;(2E)-3-(3-Methylphenyl)-2-propenal;(E)-3-(m-Tolyl)acrylaldehyde
• CAS NO: 93614-80-3
• Molecular Formula: C₁₀H₁₀O
• Molecular Weight: 146.19
• Mol File: 93614-80-3.mol
• Article Data: 32

Chemical Properties

• Boiling Point: 264.398 °C at 760 mmHg
• Flash Point: 93.547 °C
• Appearance: /
• Density: 1.015
• Vapor Pressure: 0.01mmHg at 25°C
• Refractive Index: 1.569
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-PROPENAL, 3-(3-METHYLPHENYL)-,(2E)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PROPENAL, 3-(3-METHYLPHENYL)-,(2E)(93614-80-3)
• EPA Substance Registry System: 2-PROPENAL, 3-(3-METHYLPHENYL)-,(2E)(93614-80-3)

Safety Data

• Hazardous Substances Data: 93614-80-3(Hazardous Substances Data)

Usage

General Description

2-PROPENAL, 3-(3-METHYLPHENYL)-,(2E), also known as 3-(3-methylphenyl)-2-propenal or trans-3-(3-methylphenyl)acrylaldehyde, is a chemical compound that belongs to the class of organic compounds known as cinnamic aldehydes. It is a yellow liquid with a sharp, pungent odor, and it is commonly used as a flavoring agent and aroma compound in the food and beverage industry. It is also used in the manufacture of perfumes and as a chemical intermediate in the production of various other chemicals. In addition, it has been identified as a potential intermediate in the synthesis of pharmaceuticals and other bioactive compounds. However, it is important to handle this chemical with care, as it can be an irritant to the skin, eyes, and respiratory system.

InChI:InChI=1/C10H10O/c1-9-4-2-5-10(8-9)6-3-7-11/h2-8H,1H3/b6-3+

Upstream product

• 73244-32-3 3-(3-methylphenyl)-2-propen-1-ol 
• 95416-60-7 3-(3-methylphenyl)propanal 
• 625-95-6 3-Iodotoluene 
• 107-18-6 allyl alcohol 
• 3054-95-3 acrylaldehyde diethyl acetal 
• 29978-38-9 1-(m-tolyl)prop-2-yn-1-ol 
• 620-23-5 m-tolyl aldehyde 
• 3029-79-6 3-methylcinnamic acid 
• 82444-40-4 3-(3-methylphenyl)acrylic acid methyl ester 
• 75-07-0 acetaldehyde 
• 107-02-8 acrolein 
• 108-88-3 toluene 
• 28446-71-1 3-methyl-cinnamonitrile 
• 121-44-8 triethylamine 

Downstream Products

• 97985-69-8 (2S,3R)-3-m-Tolyl-oxirane-2-carbaldehyde 
• 351536-41-9 1,1,1-trichloro-4-m-tolyl-but-3-en-2-ol 
• 113085-89-5 3-(3-tolyl)-oxirane-2-carbaldehyde 
• 113085-88-4 3-(3-tolyl)-oxirane-2-carbaldehyde 
• 1170328-06-9 C₁₈H₂₂O₃ 
• 1223035-21-9 (S)-3-(1H-pyrrol-2-yl)-3-m-tolylpropan-1-ol 
• 1275614-03-3 [Ni(CO₂CHCHC₆H₅CH₂CH₂OHNCC₆H₄CH₃C₆H₄NCOCH₂C₅H₁₀N)] 
• 1265848-24-5 cis-(4R,5S)-iso-propyl-4,5-di-m-tolylcyclopent-1-enecarboxylate 
• 1301638-20-9 C₁₈H₁₆O 
• 1301638-04-9 5-oxo-5-phenyl-3-m-tolylpentanal 
• 1322116-55-1 C₂₈H₂₆N₂O₂S 
• 1332481-99-8 (5S,6S,7R)-7-phenyl-5-m-tolyl-5,6,7,8-tetrahydroimidazo-[1,2-a]pyrimidine-6-carbaldehyde 
• 1361214-43-8 C₂₆H₃₂N₂O₃ 
• 1361214-46-1 (R)-tert-butyl 3-((2R,3S)-2-((E)-3-methylstyryl)-4-oxo-3-((S)-2-oxo-4-phenyloxazolidin-3-yl)azetidin-1-yl)-4-oxo-4-(((R)-1-phenylethyl)amino)butanoate 

Relevant articles and documents

Preparation method of alpha-deuterated olefine aldehyde

The invention relates to a preparation method of alpha-deuterated olefine aldehyde, which comprises the following steps: by taking alpha, beta-olefine aldehyde as a raw material, carrying out a reversible Michael addition mechanism under the action of deuterium water, a nucleophilic reagent and an organic catalyst to obtain an alpha-deuterated olefine aldehyde compound. The method has high selectivity, and does not generate deuterated by-products at other positions. The alpha-deuterated olefine aldehyde compound prepared by the invention has great application value, can be further widely converted to prepare mono (poly) deuterated olefin and derivatives, olefine acid, conjugated olefine aldehyde, eneyne and other compounds, and has important significance in drug synthesis.

Method for preparing olefine aldehyde by catalyzing terminal alkyne or terminal conjugated eneyne and diphosphine ligand used in method

The invention discloses a method for preparing olefine aldehyde by catalyzing terminal alkyne or terminal conjugated eneyne and a diphosphine ligand used in the method. According to the invention, indole-substituted phosphoramidite diphosphine ligand which is stable in air and insensitive to light is synthesized by utilizing a continuous one-pot method, and the indole-substituted phosphoramidite diphosphine ligand and a rhodium catalyst are used for jointly catalyzing to successfully achieve a hydroformylation reaction of aromatic terminal alkyne and terminal conjugated eneyne under the condition of synthesis gas for the first time, so that an olefine aldehyde structure compound can be rapidly and massively prepared, and particularly, a polyolefine aldehyde structure compound which is more difficult to synthesize in the prior art can be easily prepared and synthesized, and a novel method is provided for synthesis and modification of drug molecules, intermediates and chemical products.

Regioselective Silylations of Propargyl and Allyl Pivalates through Ca-Promoted Reductive C(sp3)-O Bond Cleavage

A practical protocol for the regioselective preparation of 3-phenylpropargylsilanes and 3-phenylallylsilanes in yields of 36-77 and 48-86%, respectively, from readily accessible 3-phenylpropargyl and 1-phenylallyl pivalates was developed through reductive C(sp3)-O bond cleavage. This method represents the first example of the direct application of vastly abundant calcium granules to a reductive coupling reaction. A broad range of propargylsilanes and allylsilanes are simply prepared using easy-to-handle pivalates and chlorotrimethylsilane under mild catalyst-free and additive-free conditions.