936487-27-3

Basic information

• Product Name: 4-butyl-N-(4-methylphenyl)benzenamine
• Synonyms: 4-butyl-N-(4-methylphenyl)benzenamine
• CAS NO: 936487-27-3
• Molecular Weight: 239.36
• Mol File: 936487-27-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-butyl-N-(4-methylphenyl)benzenamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-butyl-N-(4-methylphenyl)benzenamine(936487-27-3)
• EPA Substance Registry System: 4-butyl-N-(4-methylphenyl)benzenamine(936487-27-3)

Safety Data

• Hazardous Substances Data: 936487-27-3(Hazardous Substances Data)

Upstream product

• 20651-67-6 4-butyliodobenzene 
• 106-49-0 p-toluidine 
• 104-13-2 4-Butylaniline 
• 185416-14-2 4-(1-butyl)phenylmagnesium bromide 

Relevant articles and documents

Activator-Promoted Aryl Halide-Dependent Chemoselective Buchwald-Hartwig and Suzuki-Miyaura Type Cross-Coupling Reactions

Herein, we report the development of aryl halide-dependent chemoselective reactions, viz., the Buchwald-Hartwig type coupling reaction of an aryl iodide with an arylboronic acid and an aryl amine in the presence of a heterogeneous and reusable nickel catalyst and the Suzuki-Miyaura type coupling of an aryl chloride under similar conditions. Control experiments revealed that the presence of stoichiometric amounts of the phenylboronic acid/ester and aryl amine are essential for both reactions. NMR and XAFS studies suggested the formation of a boron-amine "ate"complex.

Nickel-catalyzed synthesis of diarylamines via oxidatively induced C-N bond formation at room temperature

A nickel-catalyzed oxidative coupling of zinc amides with organomagnesium compounds selectively produces diarylamines under mild reaction conditions, with tolerance for chloride, bromide, hydroxyl, ester, and ketone groups. A diamine is bis-monoarylated. A bromoaniline undergoes N-arylation followed by Kumada-Tamao-Corriu coupling in one pot. The reaction may proceed via oxidatively induced reductive elimination of a nickel species.