93684-45-8

Basic information

• Product Name: Oxazole, 4-(1,1-dimethylethyl)-4,5-dihydro-2-(2-phenylethyl)-
• CAS NO: 93684-45-8
• Molecular Formula: C15H21NO
• Molecular Weight: 231.338
• Mol File: 93684-45-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Oxazole, 4-(1,1-dimethylethyl)-4,5-dihydro-2-(2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazole, 4-(1,1-dimethylethyl)-4,5-dihydro-2-(2-phenylethyl)-(93684-45-8)
• EPA Substance Registry System: Oxazole, 4-(1,1-dimethylethyl)-4,5-dihydro-2-(2-phenylethyl)-(93684-45-8)

Safety Data

• Hazardous Substances Data: 93684-45-8(Hazardous Substances Data)

Upstream product

• 3907-02-6 2‐amino‐3,3‐dimethylbutan‐1‐ol 
• 501-52-0 3-Phenylpropionic acid 

Downstream Products

• 93684-56-1 4,5-dihydro-4-(1,1-dimethylethyl)-2-(2-phenylethyl)-3-(2-propenyl)oxazolinium 4-methylbenzenesulfonate 

Relevant articles and documents

Asymmetric Induction in the Claisen Rearrangement of N-Allylketene N,O-Acetals

Asymmetric C-C bond formation via the diastereoselective aza-Claisen rearrangement of N-allylketene N,O-acetal 1 is described.Diastereoselection noted for rearrangement 1->2 ranges from 84percent to 96percent and is a consequence of complete (Z)-N,O-acetal olefin selectivity in 1, high Cα-si-face selectivity in the rearrangement of 1 to 2, and the absence of Cα epimerization in oxazoline 2.Experiments which establish the steric bulk of the C4 appendage as a particularly important variable are also reported.Acid-catalyzed hydrolysis of rearranged oxazoline 2 completes an efficient, enantioselective synthesis of 2-substituted pent-4-enoic acid 4 and regenerates for recycling the chiral auxiliary reagent 3, initially prepared from inexpensive α-amino acids.