937743-24-3

Basic information

• Product Name: C₂₃H₂₆F₃N₃O₃
• CAS NO: 937743-24-3
• Molecular Weight: 449.473
• Mol File: 937743-24-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₆F₃N₃O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₆F₃N₃O₃(937743-24-3)
• EPA Substance Registry System: C₂₃H₂₆F₃N₃O₃(937743-24-3)

Safety Data

• Hazardous Substances Data: 937743-24-3(Hazardous Substances Data)

Upstream product

• 1736-74-9 4-trifluoromethoxybenzyl alcohol 
• 56984-32-8 5-chloro-1-methyl-1H-pyrazole-4-carboxylic acid,ethyl ester 
• 937746-41-3 C₁₅H₂₁N₃O₂ 

Relevant articles and documents

HETEROCYCLIC COMPOUND HAVING INHIBITORY ACTIVITY ON 11- -HYDROXYSTEROID DEHYDROGENASE TYPE I

Disclosed is a compound useful as a type I 11βhydroxysteroid dehydrogenase inhibitor. A compound represented by the formula: a pharmaceutically acceptable salt or solvate thereof, wherein R1 is optionally substituted alkyl or the like, one of R2 and R4 is a group of formula: -Y-R5, wherein Y is -O- or the like, R5 is substituted alkyl (the substituent is optionally substituted cycloalkyl or the like), optionally substituted branched alkyl or the like, the other of R2and R4 is hydrogen or optionally substituted alkyl, R3 is a group of formula: -C(=O)-Z-R6, wherein Z is -NR7- or -NR7-W-, R6 is optionally substituted cycloalkyl or the like, R7 is hydrogen or optionally substituted alkyl, W is optionally substituted alkylene, X is =N- or the like, with the proviso that compounds wherein R2 is 2-(morphorino)ethoxy, R3 is N-(1-adamantyl)carbamoyl and R1 is benzyl are excluded.