937812-80-1

Basic information

• Product Name: (E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one
• Synonyms: (E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one;HYR-141;Otamixaban;SynonyMs: HYR-141;gaMMa-Secretase Modulators;AMyloid-β production inhibitor;γ-Secretase Modulators;Pyrido[2,1-c][1,4]oxazin-6(1H)-one, hexahydro-7-[[3-Methoxy-4-(4-Methyl-1H-iMidazol-1-yl)phenyl]Methylene]-4-(3,4,5-trifluorophenyl)-, (4R,7E,9aS)-
• CAS NO: 937812-80-1
• Molecular Formula: C₂₆H₂₄F₃N₃O₃
• Molecular Weight: 483.4822696
• Mol File: 937812-80-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Density: 1.37
• CAS DataBase Reference: (E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one(937812-80-1)
• EPA Substance Registry System: (E)-(4R,9aS)-7-[3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]-4-(3,4,5-trifluorophenyl)hexahydropyrido[2,1-c][1,4]oxazin-6-one(937812-80-1)

Safety Data

• Hazardous Substances Data: 937812-80-1(Hazardous Substances Data)

Upstream product

• 870837-18-6 3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzaldehyde 
• 937816-18-7 [(4R,9aS)-6-oxo-4-(3,4,5-trifluorophenyl)octahydropyrido[2,1-c][1,4]oxazin-7-yl]phosphonic acid diethyl ester 

Relevant articles and documents

Prodrug of cinnamide compound

The present invention provides a most suitable prodrug of a cinnamide compound. The prodrug is represented by Formula (I) wherein Ra and Rb each denote a C1-6 alkyl group or the like; Xa denotes a methoxy group or a fluorine atom; Y denotes a phosphono group or the like; and A denotes a cyclic lactam derivative.