938-78-3

Basic information

• Product Name: Benzene, [1-(difluoromethylene)propyl]-
• CAS NO: 938-78-3
• Molecular Formula: C10H10F2
• Molecular Weight: 168.186
• Mol File: 938-78-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzene, [1-(difluoromethylene)propyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, [1-(difluoromethylene)propyl]-(938-78-3)
• EPA Substance Registry System: Benzene, [1-(difluoromethylene)propyl]-(938-78-3)

Safety Data

• Hazardous Substances Data: 938-78-3(Hazardous Substances Data)

Upstream product

• 75-61-6 dibromodifluoromethane 
• 93-55-0 1-phenyl-propan-1-one 
• 384-64-5 3,3,3-trifluoro-2-phenylpropene 
• 917-54-4 methyllithium 
• 1235751-66-2 3-ethyl-3-phenyl-3H-diazirine 
• 115262-01-6 [bromo(difluoro)methyl]-trimethyl-silane 
• 81290-20-2 (trifluoromethyl)trimethylsilane 

Relevant articles and documents

Addition of organolithium reagents to α-(trifluoromethyl)styrene: Concise synthesis of functionalised gem-difluoroalkenes

The treatment of α-(trifluoromethyl)styrene with organolithium reagents results in the selective formation of gem-difluoroalkenes in good-to-excellent yields. This reaction has been applied to the synthesis of 3-gem-difluoro-2-phenylallylic amines and oth

Direct Difluoromethylenation of Carbonyl Compounds by Using TMSCF3: The Right Conditions

A deoxygenative difluoromethylenation of carbonyl compounds has been developed by using readily available, inexpensive trifluoromethyltrimethylsilane, LiI, and PPh3. The presence of the Li+ion prevents the unproductive exhaustion of trifluoromethyltrimethylsilane (TMSCF3) by keeping the soluble free fluoride concentration in the reaction medium under control. The strategy of combining solvents to increase the reactivity and thereby reduce the reaction temperature and time is disclosed.

A Concise Synthesis of Functionalised gem-Difluoroalkenes via the Addition of Organolithium Reagents to α-Trifluoromethylstyrene

The treatment of α-trifluoromethyl styrene with organolithium reagents results in the selective formation of gem-difluoroalkenes in good to excellent yield.This reaction has been applied to the synthesis of a range functionalised gem-difluoroalkenes. - Ke