93960-20-4 Usage
General Description
L-3-Pyridylalanine hydrochloride is a chemical compound consisting of the amino acid L-3-Pyridylalanine and hydrochloride. It is a derivative of phenylalanine, an essential amino acid that the body requires for various biological functions. L-3-Pyridylalanine hydrochloride is commonly used in the synthesis of peptides and proteins for research purposes, and it has been studied for its potential pharmaceutical applications, particularly in the development of novel drugs targeting specific pathways in the body. L-3-Pyridylalanine hydrochloride may also have applications in the field of neuroscience and neuropharmacology, as it could potentially influence neurotransmission and receptor activity in the brain. Overall, L-3-Pyridylalanine hydrochloride represents a valuable chemical for both scientific and potentially therapeutic uses.
Check Digit Verification of cas no
The CAS Registry Mumber 93960-20-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,9,6 and 0 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 93960-20:
(7*9)+(6*3)+(5*9)+(4*6)+(3*0)+(2*2)+(1*0)=154
154 % 10 = 4
So 93960-20-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2O2.ClH/c1-6(8(11)12)10-7-3-2-4-9-5-7;/h2-6,10H,1H3,(H,11,12);1H/t6-;/m0./s1
93960-20-4Relevant articles and documents
Anthranilic acid based CCK1 receptor antagonists: Preliminary investigation on their second "touch point"
Varnavas, Antonio,Lassiani, Lucia,Valenta, Valentina,Mennuni, Laura,Makovec, Francesco,Hadjipavlou-Litina, Dimitra
, p. 563 - 581 (2007/10/03)
In this phase of structure-affinity relationship study of VL-0395, a new anthranilic acid based CCK1 selective antagonist, we propose a series of unnatural aminoacidic derivatives. The result of this work is the identification of a new CCK ligand, which possesses an affinity (IC50 = 35 nm) one order of magnitude greater than the lead and, as a general rule, it points out how the hypothesized receptorial pocket which accommodates the Phe residue allows much more structural modification than that interacting with the N-terminal group. Hence, the modification of the C-terminal pharmacophoric group of our lead VL-0395 can not only enhance the affinity of anthranilic acid derivatives but can modulate the selectivity for one CCK receptor subtype or afford mixed antagonists.
