93978-65-5

Basic information

• Product Name: Benzamide, N-[4-hydroxy-3-[(4-methyl-1-piperazinyl)methyl]phenyl]-4-isothiocyanato -
• CAS NO: 93978-65-5
• Molecular Formula: C20H22N4O2S
• Molecular Weight: 382.486
• Mol File: 93978-65-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzamide, N-[4-hydroxy-3-[(4-methyl-1-piperazinyl)methyl]phenyl]-4-isothiocyanato -(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-[4-hydroxy-3-[(4-methyl-1-piperazinyl)methyl]phenyl]-4-isothiocyanato -(93978-65-5)
• EPA Substance Registry System: Benzamide, N-[4-hydroxy-3-[(4-methyl-1-piperazinyl)methyl]phenyl]-4-isothiocyanato -(93978-65-5)

Safety Data

• Hazardous Substances Data: 93978-65-5(Hazardous Substances Data)

Upstream product

• 122-04-3 4-nitro-benzoyl chloride 
• 76226-58-9 4-amino-2-((4-methylpiperazin-1-yl)methyl)phenol 
• 17183-43-6 2-(4-methyl-piperazin-1-ylmethyl)-4-(4-nitro-benzoylamino)-phenol 

Relevant articles and documents

Studies in Potential Filaricides: Part XVI - Synthesis of 2,4-Disubstituted Aminophenols and Related Benzophenones as Amodiaquine Analogs

A series of 2,4-disubstituted aminophenols (6-16, 18, 19, 22, 25) and substituted benzophenones (17, 20, 21, 23, 24, 33-35) and benzimidazoles (26-31) have been prepared starting from 2-substituted 4-aminophenols (1-3) or 4-chloro-4'-hydroxy-3-nitrobenzophenone (5).The mechanism of formation of benzimidazol-2-one by the reaction of o-phenylenediamine with 1,3-dicarbethoxy-S-methylisothiourea in refluxing DMF is also discussed.A number of compounds have been tested for their antifilarial, antihookworm and cestodicidal activities against Litomosoides carnii, Ancylostoma ceylanicum and Hymenolepis nana respectively in rodents but none of them shows any significant activity.