94-31-5

Basic information

• Product Name: 4-((2-Chloroethyl)(methyl)amino)benzaldehyde
• Synonyms: 4-((2-chloroethyl)(methyl)amino)benzaldehyde;4-[N-METHYL-N-(2-CHLOROETHYL)] AMINO BENZALDEHYDE;4-(N-METHYL-N-(BETA-CHLOROETHYL))AMINOBENZALDEHYDE;4-(N-METHYL-N-CHLOROETHYL)AMINOBENZALDEHYDE;4-[(2-chloroethyl)methylamino]-benzaldehyd;p-[(2-chloroethyl)methylamino]benzaldehyde;N-Methyl-N-Chloroethyl-p-Amino Benzaldehyde;N-Methyl-N-Chloroethyl-4-Amino Benzaldehyde
• CAS NO: 94-31-5
• Molecular Formula: C₁₀H₁₂ClNO
• Molecular Weight: 197.66
• EINECS: 202-321-3
• Product Categories: Intermediates of Dyes and Pigments
• Mol File: 94-31-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 70 °C
• Boiling Point: 328.7 °C at 760 mmHg
• Flash Point: 152.6 °C
• Appearance: /
• Density: 1.183 g/cm^>3
• Vapor Pressure: 0.000186mmHg at 25°C
• Refractive Index: 1.595
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 1.47±0.50(Predicted)
• CAS DataBase Reference: 4-((2-Chloroethyl)(methyl)amino)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((2-Chloroethyl)(methyl)amino)benzaldehyde(94-31-5)
• EPA Substance Registry System: 4-((2-Chloroethyl)(methyl)amino)benzaldehyde(94-31-5)

Safety Data

• Hazardous Substances Data: 94-31-5(Hazardous Substances Data)

Usage

General Description

4-((2-Chloroethyl)(methyl)amino)benzaldehyde, also known as N-(2-Chloroethyl)-N-methyl-3-aminobenzaldehyde, is a chemical compound with the formula C9H10ClNO. It is a pale yellow to brown liquid with a strong, pungent odor. This chemical is used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is a potential mutagen and carcinogen, and exposure to this compound should be carefully controlled in laboratory and industrial settings. It is important to handle and store this compound with appropriate safety measures to minimize the risk of exposure and adverse health effects.

InChI:InChI=1/C10H12ClNO/c1-12(7-6-11)10-4-2-9(8-13)3-5-10/h2-5,8H,6-7H2,1H3

Upstream product

• 1669-85-8 N-(2-chloroethyl)-N-methylaniline 
• 68-12-2 N,N-dimethyl-formamide 
• 1201-91-8 4-(N-methyl-N-hydroxyethylamino)benzaldehyde 
• 59689-19-9 1-(2-aminophenyl)propan-1-ol 
• 93-61-8 N-methyl-N-phenylformamide 
• 93-90-3 N-(2-hydroxyethyl)-N-methylaminobenzene 
• 10025-87-3 trichlorophosphate 

Downstream Products

• 62783-77-1 2-{4-[(2-chloro-ethyl)-methyl-amino]-trans-styryl}-1,3,3-trimethyl-3H-indolium; iodide 
• 1201-91-8 4-(N-methyl-N-hydroxyethylamino)benzaldehyde 
• 76578-89-7 2-(4-formyl-N-methyl-anilino)-ethanesulfonic acid 
• 1235485-85-4 N-(3-DOTA-amidopropyl)-N-[3-[[[4-[(2-chloroethyl)methylamino]phenyl]methyl]amino]propyl]-N,N-dimethylammonium triuoroacetate 
• 911712-36-2 CH₃O₄S^(1-)*C₂₁H₂₂ClN₂⁽¹⁺⁾ 
• 911712-28-2 CH₃O₄S^(1-)*C₁₇H₂₀ClN₂⁽¹⁺⁾ 
• 911709-30-3 C₂₂H₂₆N₂O₃S₂ 
• 101004-65-3 {5-[1-{4-[(2-Chloro-ethyl)-methyl-amino]-phenyl}-meth-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-acetic acid 
• 73268-78-7 3t-{4-[methyl-(2-chloro-ethyl)-amino]-phenyl}-2-cyano-acrylic acid ethyl ester 
• 1135026-66-2 2-[(4-formylphenyl)(methyl)-amino]ethyl imidothiocarbamate 
• 77544-42-4 C₂₈H₂₄ClN₂O⁽¹⁺⁾*CH₃O₄S^(1-) 

Relevant articles and documents

A 4 - (N - methyl - N - sulfo ethyl) amino formaldehyde sodium synthesis method

The present invention discloses a 4-(N-methyl-N-sulfoethyl)aminobenzaldehyde sodium salt synthesis method, which comprises: adding N-methyl-N-hydroxyethyl aniline and a chlorine-containing oxide to an organic solvent to carry out a substitution reaction so as to generate N-methyl-N-chloroethylaniline, carrying out a Vilsmeier-Haack reaction of the N-methyl-N-chloroethylaniline, disubstituted formamide and phosphorus oxychloride to generate N-methyl-N-chloroethyl-4-aminobenzaldehyde, and carrying out a sulfonation reaction of the N-methyl-N-chloroethyl-4-aminobenzaldehyde and a sulfonation agent in an alkaline solution to generate the 4-(N-methyl-N-sulfoethyl)aminobenzaldehyde sodium salt. The method of the present invention has characteristics of cheap and readily available raw materials and simple process, and is suitable for large-scale industrial production.

Nucleic acid-immobilized substrate

By immobilizing identical or different nucleic acids in a plurality of dot-like areas on a carrier which comprises a base material and compound carried on the base material, the compound having one or more alkylating groups, through intermediary of the alkylating group, a nucleic acid-immobilized substrate on which nucleic acids are firmly immobilized in fine dot area without reference to chain length of nucleic acids is provided, which enables efficiently introducing the nucleic acids onto the base material in a simple manner and can be produced with a simple apparatus.