94-78-0 Usage
Chemical Properties
Phenazopyridine is a red crystalline compound. Slightly soluble in water.
Uses
An azo dye used in treatment of urinary tract infections. 3-(Phenylazo)-2,6-pyridinediamine is used as an analgesic (urinary tract).
Definition
ChEBI: A diaminopyridine that is 2,6-diaminopyridine substituted at position 3 by a phenylazo group. A local anesthetic that has topical analgesic effect on mucosa lining of the urinary tract. Its use is limited by problems with toxicity (primarily blood disorder
) and potential carcinogenicity.
Brand name
Pyridium (Parke-Davis);Azo gantrisin;Azodine;Phenazo;Pyridiate;Pyronium;Sedural.
World Health Organization (WHO)
Phenazopyridine, an azo dye, was introduced in the 1950s as a
urinary antiseptic. It was withdrawn in Greece in 1984 on grounds that it has a
carcinogenic potential but it remains available in other countries, most frequently
as a constituent of combination products.
Safety Profile
Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental neoplastigenic data. Used as a local anesthetic. When heated to decomposition it emits toxic fumes of NOx.
Incompatibilities
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.
Check Digit Verification of cas no
The CAS Registry Mumber 94-78-0 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 9 and 4 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 94-78:
(4*9)+(3*4)+(2*7)+(1*8)=70
70 % 10 = 0
So 94-78-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H5N2/c7-8-6-4-2-1-3-5-6/h1-5H
94-78-0Relevant articles and documents
Phenazopyridine cocrystal and salts that exhibit enhanced solubility and stability
Tao, Qian,Chen, Jia-Mei,Ma, Lei,Lu, Tong-Bu
body text, p. 3144 - 3152 (2012/08/14)
One phenazopyridine monohydrate (1?H2O), one cocrystal of phenazopyridine with phthalimide (2), and three salts of phenazopyridine with benzoic acid (3), 4-hydroxyphenylacetic acid (4), and scaaharin (5) were synthesized, and their structures w
