941294-54-8

Basic information

• Product Name: 5-Bromo-3-cyano-2-methoxypyridine
• Synonyms: 5-Bromo-2-methoxynicotinonitrile;5-bromo-2-methoxypyridine-3-carbonitrile;5-Bromo-2-methoxypyridine-3-carbonitrile, 5-Bromo-3-cyano-2-methoxypyridine;5-Bromo-2-methoxy-3-pyridinecarbonitrile;3-Bromo-5-cyano-6-methoxypyridine;5-Bromo-2-methoxynicotinonitrile98%
• CAS NO: 941294-54-8
• Molecular Formula: C₇H₅BrN₂O
• Molecular Weight: 213.04
• Product Categories: blocks;Bromides;Carboxes;Pyridines
• Mol File: 941294-54-8.mol
• Article Data: 8

Chemical Properties

• Melting Point: 110-115°C
• Boiling Point: 267℃
• Flash Point: 115℃
• Appearance: /
• Density: 1.65
• Vapor Pressure: 0.00863mmHg at 25°C
• Refractive Index: 1.587
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -2.40±0.20(Predicted)
• CAS DataBase Reference: 5-Bromo-3-cyano-2-methoxypyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-3-cyano-2-methoxypyridine(941294-54-8)
• EPA Substance Registry System: 5-Bromo-3-cyano-2-methoxypyridine(941294-54-8)

Safety Data

• Hazard Codes: Xi,T
• Statements: 25-36/37/38
• Safety Statements: 26-36-45
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 941294-54-8(Hazardous Substances Data)

Usage

General Description

5-Bromo-3-cyano-2-methoxypyridine is a chemical compound with the molecular formula C7H5BrN2O. It is a pyridine derivative that is commonly used in organic synthesis and pharmaceutical research. 5-Bromo-3-cyano-2-methoxypyridine is known for its ability to act as a building block in the synthesis of various biologically active molecules, such as kinase inhibitors and antiviral agents. 5-Bromo-3-cyano-2-methoxypyridine has also been studied for its potential use in the treatment of cancer and other diseases. Its unique chemical properties and versatile applications make it a valuable tool for scientists in the field of medicinal chemistry and drug development.

InChI:InChI=1/C7H5BrN2O/c1-11-7-5(3-9)2-6(8)4-10-7/h2,4H,1H3

Upstream product

• 7254-34-4 2-methoxy-3-cyanopyridine 
• 6602-54-6 2-chloro-3-pyridinecarbonitrile 

Downstream Products

• 1392150-47-8 5-(3,5-difluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-amine 
• 1443776-44-0 2-methoxy-5-{4-[3-((R)-3-methyl-piperazine-1-carbonyl)-phenyl]-quinazolin yl}-nicotinonitrile 
• 1431541-32-0 2-methoxy-5-{4-[3-((R)-3-methylpiperazine-1-carbonyl)phenyl]quinazolin-6-yl}nicotinonitrile 
• 1431540-99-6 5-{4-[3-(4-acetyl-piperazine-1-carbonyl)-phenyl]-quinazolin-6-yl}-2-methoxy-nicotinonitrile 
• 1073354-05-8 2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carbonitrile 

Relevant articles and documents

Uses for whitening material of 4-(4-methylpiperazin-1-yl)-N-(5-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl)benzamide derivatives, or pharmaceutical acceptable salt thereof

The present invention relates to uses for a whitening material of a 4-(4-methylpiperazin-1-yl)-N-(5-(pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl)benzamide derivative, or a pharmaceutically acceptable salt thereof. A composition for whitening provided in

Derivatives of azaindoles or diazaindoles for treating pain

The present invention relates to a compound of following formula (I): or a pharmaceutically acceptable salt or solvate of same, a tautomer of same, or a stereoisomer or mixture of stereoisomers of same in any proportions, such as a mixture of enantiomers, notably a racemic mixture; for use in the treatment of pain.

DERIVATIVES OF AZAINDAZOLE OR DIAZAINDAZOLE TYPE FOR TREATING A CANCER OVEREXPRESSING TRK

The present invention relates to a compound of following formula (I) or a pharmaceutically acceptable salt or solvate of same, a tautomer of same, or a stereoisomer or mixture of stereoisomers of same in any proportions, such as a mixture of enantiomers, notably a racemic mixture, as well as pharmaceutical composition comprising such a compound, for use in the treatment of a cancer associated with the overexpression of at least one Trk protein.