941575-71-9 Usage
Description
3-(5-BroMo-1-Methyl-1H-indol-3-yl)-4-(benzofuran-3-yl)pyrrole-2,5-dione is a complex organic compound characterized by its unique molecular structure. It features a pyrrole-2,5-dione core with a 5-bromo-1-methyl-1H-indol-3-yl group at the 3-position and a benzofuran-3-yl group at the 4-position. 3-(5-BroMo-1-Methyl-1H-indol-3-yl)-4-(benzofuran-3-yl)pyrrole-2,5-dione has potential applications in various fields due to its specific chemical properties and interactions.
Uses
Used in Pharmaceutical Industry:
3-(5-BroMo-1-Methyl-1H-indol-3-yl)-4-(benzofuran-3-yl)pyrrole-2,5-dione is used as a potent GSK-3 inhibitor for the therapeutic treatment of spinal muscular atrophy. Its ability to inhibit the activity of glycogen synthase kinase 3 (GSK-3) makes it a promising candidate for the development of drugs targeting this enzyme, which plays a crucial role in the progression of spinal muscular atrophy.
Check Digit Verification of cas no
The CAS Registry Mumber 941575-71-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,1,5,7 and 5 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 941575-71:
(8*9)+(7*4)+(6*1)+(5*5)+(4*7)+(3*5)+(2*7)+(1*1)=189
189 % 10 = 9
So 941575-71-9 is a valid CAS Registry Number.
941575-71-9Relevant articles and documents
3-BENZOFURANYL-4-INDOLYL MALEIMIDES AS POTENT GSK3 INHIBITORS FOR NEUROGENERATIVE DISORDERS
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Page/Page column 66-67, (2008/12/06)
Compounds of formula (I): and pharmaceutically acceptable salts, esters and solvates thereof, where variables are defined in the specification, useful generally as inhibitors of protein kinases and particularly useful for inhibition of GSK-3. Pharmaceutically compositions and medicaments containing a compound of the invention are provided. The invention provides methods of treatment of protein kinase-related disease, disorders or conditions. The invention provides methods of treatment of GSK-3-related diseases, disorders or conditions. More specifically, methods of treatment of bipolar disorder, including mania, schizophrenia, stroke, epilepsy, motor neuron disease, cranial or spinal trauma, neurodegenerative disorders, including multiple sclerosis (MS), Alzheimer's disease, Fragile X syndrome, autism, Huntington's disease, Parkinson's
