942474-66-0 Usage
Chemical class
Piperazine derivative
Explanation
It belongs to a class of chemical compounds that are derived from piperazine, a heterocyclic amine.
Explanation
The compound has a piperazine ring with substituents attached to it.
Explanation
A methylsulfonyl group is attached to the phenyl ring at the 4-position.
Explanation
The phenyl ring is a part of the molecule and is connected to the piperazine ring.
Explanation
The compound may have uses in the development of pharmaceutical agents and drug candidates due to its structural features and functional groups.
Explanation
It may be used as a starting material or intermediate in the synthesis of various pharmaceutical agents.
Explanation
The compound may possess biological activities and could be studied for its potential effects on different biological targets.
Explanation
Additional research and development may be required to fully understand the compound's potential in the field of medicine and drug discovery.
Structural feature
Substituted piperazine
Functional group
Methylsulfonyl group
Phenyl ring
Attached to the piperazine
Potential applications
Pharmacological and therapeutic
Building block
Synthesis of pharmaceutical agents
Biological activities
Possible effects on enzymes, receptors, and ion channels
Research and development
Further study needed
Check Digit Verification of cas no
The CAS Registry Mumber 942474-66-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,4,2,4,7 and 4 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 942474-66:
(8*9)+(7*4)+(6*2)+(5*4)+(4*7)+(3*4)+(2*6)+(1*6)=190
190 % 10 = 0
So 942474-66-0 is a valid CAS Registry Number.
942474-66-0Relevant articles and documents
Nickel-Catalyzed Amination of (Hetero)aryl Halides Facilitated by a Catalytic Pyridinium Additive
Han, Dongyang,Li, Sasa,Xia, Siqi,Su, Mincong,Jin, Jian
supporting information, p. 12349 - 12354 (2020/09/09)
An efficient and operationally simple Ni-catalyzed amination protocol has been developed. This methodology features a simple NiII salt, an organic base and catalytic amounts of both a pyridinium additive and Zn metal. A diverse number of (hetero)aryl halides were coupled successfully with primary and secondary alkyl amines, and anilines in good to excellent yields. Similarly, benzophenone imine gave the corresponding N-arylation product in an excellent yield.
CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS
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Page/Page column 54-55, (2009/03/07)
The present invention relates to compounds of formula (I) for treating diseases associated with cysteine protease activity. The compounds are reversible inhibitors of cysteine proteases, including cathepsins B, K, C, F, H, L, O, S, W and X. Of particular interest are diseases associated with Cathepsin K.
N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF
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Page/Page column 86, (2008/06/13)
The present invention is related to N-hydroxyamide derivatives of Formula (I) and use thereof, in particular for the treatment and/or prophylaxis of autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, cancer, respiratory diseases and fibrosis, including multiple sclerosis, arthritis, emphysema, chronic obstructive pulmonary disease, liver and pulmonary fibrosis.
