945389-16-2Relevant articles and documents
Piperidine amides as 11β-hydroxysteroid dehydrogenase type 1 inhibitors
Flyrén, Katarina,Bergquist, Lars O.,Castro, Victor M.,Fotsch, Christopher,Johansson, Lars,St. Jean Jr., David J.,Sutin, Lori,Williams, Meredith
, p. 3421 - 3425 (2008/02/08)
A series of piperidine amide inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) were identified via modifications of the HTS hit compound 1. The synthesis, in vitro biological evaluation, and structure-activity relationship of these co