945771-96-0

Basic information

• Product Name: BNC105P
• Synonyms: BNC105P;BNC105P(BNC-105P);[6-Methoxy-2-methyl-7-(phosphonooxy)-3-benzofuranyl](3,4,5-trimethoxyphenyl)methanone sodium salt;Methanone, [6-methoxy-2-methyl-7-(phosphonooxy)-3-benzofuranyl](3,4,5-trimethoxyphenyl)-, disodium salt;JQYGYJSOLNMXOF-UHFFFAOYSA-N
• CAS NO: 945771-96-0
• Molecular Formula: C20H19Na2O10P
• Molecular Weight: 496.312161
• Mol File: 945771-96-0.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BNC105P(CAS DataBase Reference)
• NIST Chemistry Reference: BNC105P(945771-96-0)
• EPA Substance Registry System: BNC105P(945771-96-0)

Safety Data

• Hazardous Substances Data: 945771-96-0(Hazardous Substances Data)

Usage

General Description

BNC105P is a novel small molecule anticancer agent that acts as a vascular disrupting agent (VDA) and tubulin polymerization inhibitor. It has shown promising anti-tumor activity in preclinical models and is currently undergoing clinical trials for the treatment of various cancer types, including solid tumors and hematologic malignancies. BNC105P disrupts the blood supply to tumors by targeting and destroying the endothelial cells that line the blood vessels, thereby cutting off the tumor's oxygen and nutrient supply. Additionally, it also disrupts the microtubule network within cancer cells, leading to cell cycle arrest and apoptosis. The potential of BNC105P as an anti-cancer agent makes it a promising candidate for further evaluation in clinical settings.