94614-84-3 Usage
Imidazole ring
A five-membered aromatic ring with three carbon atoms and two nitrogen atoms.
2-Bromoethyl substituent
A bromine atom attached to an ethyl group (two carbon atoms with a hydrogen atom) that is attached to the imidazole ring.
Molecular weight
200.07 g/mol, representing the mass of one mole of the compound.
Organic compound
A compound containing carbon atoms.
Building block in organic synthesis
Used as a starting material to create more complex molecules in the synthesis of pharmaceuticals.
Used in pharmaceuticals
Commonly used in the preparation of antifungal and antiparasitic drugs.
Reagent in chemical reactions
Used in cross-coupling and nucleophilic substitution reactions.
Monohydrobromide form
Indicates the presence of a bromine atom and a hydrogen atom in the compound, which can affect its chemical properties and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 94614-84-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,4,6,1 and 4 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 94614-84:
(7*9)+(6*4)+(5*6)+(4*1)+(3*4)+(2*8)+(1*4)=153
153 % 10 = 3
So 94614-84-3 is a valid CAS Registry Number.
94614-84-3Relevant articles and documents
Novel antiasthmatic agents with dual activities of thromboxane A2 synthetase inhibition and bronchodilation. 1. 2-[2-(1-imidazolyl)alkyl]- 1(2H)-phthalazinones
Yamaguchi,Kamei,Koga,Akima,Kuroki,Ohi
, p. 4052 - 4060 (2007/10/02)
A number of 4-substituted 2-[ω-(1-imidazolyl)alkyl]-1(2H)-phthalazinones were synthesized in order to develop agents possessing both thromboxane A2 synthetase inhibitory and bronchodilatory activities. The pharmacological evaluation of these compounds disclosed that they have both activities to various extents. Both activities were slightly dependent on the length of the 2-substituents and largely affected by the nature of the 4-substituents. Compounds bearing phenyl and thienyl groups exhibited relatively high and well-rounded activities. Among these compounds, 12j and 15f were found to be the most effective agents having well-rounded activities in vitro and in vivo. Introduction of a carboxyl group reduced both activities contrary to our expectation. 4-(3-Pyridyl)phthalazinone 18b was of particular interest because of unexpectedly high in vivo activities in spite of an absence of significant in vitro activities.
