94666-11-2

Basic information

• Product Name: Benzenesulfonamide, 2-methoxy-5-[2-[[2-(2-methoxyphenoxy)ethyl]amino]propyl]-
• CAS NO: 94666-11-2
• Molecular Formula: C19H26N2O5S
• Molecular Weight: 394.492
• Mol File: 94666-11-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, 2-methoxy-5-[2-[[2-(2-methoxyphenoxy)ethyl]amino]propyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 2-methoxy-5-[2-[[2-(2-methoxyphenoxy)ethyl]amino]propyl]-(94666-11-2)
• EPA Substance Registry System: Benzenesulfonamide, 2-methoxy-5-[2-[[2-(2-methoxyphenoxy)ethyl]amino]propyl]-(94666-11-2)

Safety Data

• Hazardous Substances Data: 94666-11-2(Hazardous Substances Data)

Upstream product

• 122-84-9 4-methoxybenzyl methyl ketone 
• 1836-62-0 2-(2-methoxy-phenoxy)-ethylamine 
• 80223-79-6 2-methoxy-5-(2-oxopropyl)benzenesulfonyl chloride 
• 116091-63-5 2-methoxy-5-(2-oxopropyl)benzenesulfonamide 

Relevant articles and documents

Novel phenoxyalkylamine derivatives. VII. Synthesis and pharmacological activities of 2-alkoxy-5-[(phenoxyalkylamino)alkyl]benzenesulfonamide derivatives

To find a novel α-blocker with high α-blocking selectivity against dopamine D2-receptor affinity, we performed structural modification of the alkylene chains and the substituents on two benzene rings of 2-alkoxy-5-[(phenoxyalkylamino)alkyl]benzenesulfonamide derivatives. The modification of the alkylene chain between the amino moiety in the center of the molecule and the benzene ring (ring A) was found to be the most significant. 5-[2-[[2-(5-Fluoro-2-methoxyphenoxy)ethyl]amino]propyl]-2-methoxybenze nesulfonamide (II-4), which possesses 1-methylethyl as the alkylene chain, exhibited high α-blocking selectivity as well as potent α-blocking activity.