94921-62-7

Basic information

• Product Name: 1-O-(4-nitrophenyl)-2,3,4-tri-O-acetyl-β-D-xylopyranoside
• CAS NO: 94921-62-7
• Molecular Weight: 397.339
• Mol File: 94921-62-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1-O-(4-nitrophenyl)-2,3,4-tri-O-acetyl-β-D-xylopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: 1-O-(4-nitrophenyl)-2,3,4-tri-O-acetyl-β-D-xylopyranoside(94921-62-7)
• EPA Substance Registry System: 1-O-(4-nitrophenyl)-2,3,4-tri-O-acetyl-β-D-xylopyranoside(94921-62-7)

Safety Data

• Hazardous Substances Data: 94921-62-7(Hazardous Substances Data)

Upstream product

• 62446-93-9 1,2,3,4-tetra-O-acetyl-D-xylopyranose 
• 100-02-7 4-nitro-phenol 
• 4049-33-6 tetra-O-acetyl-β-D-xylopyranose 
• 87-72-9 D-Xylose 
• 3945-26-4 α-D-xylopyranosyl fluoride 
• 108-24-7 acetic anhydride 
• 2001-96-9 p-nitrophenyl β-D-xylopyranoside 
• 3068-31-3 1-bromo-2,3,4-tri-O-acetyl-α-D-xylopyranose 
• 3068-31-3 2,3,4-tri-O-acetyl-α-D-xylopyranosyl bromide 
• 1233-03-0 1,2,3,4-tetra-O-acetyl-α-L-arabinopyranose 

Downstream Products

• 1195341-88-8 (4-amino-phenyl)-β-L-arabinopyranoside 
• 144683-70-5 p-nitrophenyl O-β-D-galactopyranosyl-(1->4)-β-D-xylopyranoside 
• 144683-69-2 p-nitrophenyl O-β-D-galactopyranosyl-(1->3)-β-D-xylopyranoside 
• 17306-77-3 4-aminophenyl 2,3,4-tri-O-acetyl-β-D-xylopyranoside 
• 173468-31-0 4-nitrophenyl O-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)-(1<*>4)-bis4)>-2,3-di-O-benzoyl-β-D-xylopyranoside 
• 173468-25-2 4-nitrophenyl O-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)-(1<*>4)-O-(2,3-di-O-acetyl-β-D-xylopyranosyl)-(1<*>4)-2,3-di-O-benzoyl-β-D-xylopyranoside 
• 173468-14-9 4-nitrophenyl O-(2,3,4-tri-O-acetyl-β-D-xylopyranosyl)-(1<*>4)-2,3-di-O-benzoyl-β-D-xylopyranoside 
• 173468-35-4 4-nitrophenyl O-β-D-xylopyranosyl-(1<*>4)-bis4)>-β-D-xylopyranoside 
• 173468-11-6 4-nitrophenyl 2,3-di-O-benzoyl-4-O-chloroacetyl-β-D-xylopyranoside 
• 173468-29-6 4-nitrophenyl O-β-D-xylopyranosyl-(1<*>4)-O-β-D-xylopyranosyl-(1<*>4)-β-D-xylopyranoside 
• 173468-12-7 4-nitrophenyl 2,3-di-O-benzoyl-β-D-xylopyranoside 
• 173468-09-2 4-nitrophenyl 4-O-chloroacetyl-β-D-xylopyranoside 
• 6819-07-4 p-nitrophenyl β-D-xylopyranosyl-(1->4)-β-D-xylopyranoside 
• 162088-88-2 1-O-(4-nitrophenyl)-2,3-di-O-acetyl-β-D-xylopyranoside 

Relevant articles and documents

Propargyl-containing xylose and synthesis method thereof

The invention discloses propargyl-containing xylose and a preparation method thereof. The method comprises the following steps: using D-xylose as a raw material, carrying out full acetyl protection onthe D-xylose, introducing p-nitrophenoxy into a first position of an obtained compound, and removing acetyl to obtain a compound A; introducing tert-butyl dimethyl into the position 2, the position 3or the position 4 of the obtained compound A to obtain a compound B, a compound C and a compound D, and separating the compound B, the compound C and the compound D; and respectively carrying out acetyl protection on hydroxyl groups of the compound B, the compound C and the compound D, then removing the tert-butyl dimethyl, and respectively introducing propargyl into the position 2, the position3 and the position 4 to obtain the propargyl-containing xylose. According to the method disclosed by the invention, the propargyl is selectively connected to xylose for the first time by using a method for carrying out occupying by using tert-butyl dimethyl (TBS), so that a platform is provided for subsequent connection of the xylose to protein or amino acid, and a foundation is laid for biological research in the future.

Synthesis and inhibitory activity evaluation of 2,6-disubstituted purine derivatives

A series of novel 2,6-disubstituted purine derivatives were designed and synthesized from 2,6-dichloropurine. The structures of target compounds were determined by 1H-NMR, 13C-NMR, and HRMS. The synthesized compounds were evaluated for their inhibitory activities against lung cancer cell lines of A549 and liver cancer cell lines of Bel-7402. 2-(4-Benzyloxy-phenylamino)-6-(cyclohexylamino)purine(3), 2-(4-chloro-phenylamino)-6-(n-butylamino)purine (5), 2-(4-morpholinoamino)-6-(4-hydroxy-phenylamino)purine (9), and 2-(4-O-galactosyl-phenylamino)-6-(cyclohexylamino)purine (12) exhibited moderate inhibitory activity.

Glycosynthase-Mediated Assembly of Xylanase Substrates and Inhibitors

An exo-β-xylosidase mutant with glycosynthase activity was created to aid in the synthesis of xylanase substrates and inhibitors. Simple monosaccharides were easily elaborated into di-, tri- and tetrasaccharides by using this enzyme. Some products proved