95015-72-8Relevant articles and documents
Synthesis, enzyme assays and molecular docking studies of fluorinated bioisosteres of santacruzamate a as potential HDAC tracers
Ahamed, Muneer,Vermeulen, Koen,Schnekenburger, Michael,Moltzau, Lise Román,Levy, Finn Olav,Marton, János,Froeyen, Mathy,Olberg, Dag Erlend,Diederich, Marc,Bormans, Guy
, p. 787 - 797 (2017/08/07)
Background: Histone deacetylases (HDACs) emerged as important epigenetic regulators of gene expression. Method: In order to identify potential positron emission tomography (PET) tracers for imaging HDACs, we evaluated in vitro and in cellulo activities of
SANTACRUZAMATE A COMPOSITIONS AND ANALOGS AND METHODS OF USE
-
Page/Page column 50, (2014/02/16)
The compositions and methods described herein relate generally to Santacruzamate A compositions and analogs, which, among other features, are useful as histone deacetylase (HDAC) inhibitors.