950604-72-5 Usage
Description
Ethyl 1-(thiophen-2-yl)cyclopropanecarboxylate is a chemical compound with the formula C11H12O2S. It is an ester derived from ethyl alcohol and cyclopropanecarboxylic acid, featuring a thiophene ring substituent. ethyl 1-(thiophen-2-yl)cyclopropanecarboxylate is known for its role in organic synthesis and pharmaceutical research and development.
Used in Organic Synthesis:
Ethyl 1-(thiophen-2-yl)cyclopropanecarboxylate is used as a building block in organic synthesis for creating more complex molecules. Its unique structure allows it to be a versatile component in the formation of various organic compounds.
Used in Pharmaceutical Research and Development:
In the pharmaceutical industry, ethyl 1-(thiophen-2-yl)cyclopropanecarboxylate is used as a key intermediate in the synthesis of potential drug candidates. The presence of the thiophene ring in its structure makes it a compound of interest for the development of novel drugs with potential therapeutic applications.
Used in Drug Development:
Ethyl 1-(thiophen-2-yl)cyclopropanecarboxylate is utilized in drug development as a precursor for the creation of new pharmaceuticals. Its unique properties and the presence of the thiophene ring contribute to its potential in developing drugs with novel mechanisms of action and therapeutic benefits.
It is important to handle ethyl 1-(thiophen-2-yl)cyclopropanecarboxylate with care due to its potential health and environmental hazards. Proper safety measures should be taken during its use in research and development processes.
Check Digit Verification of cas no
The CAS Registry Mumber 950604-72-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,0,6,0 and 4 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 950604-72:
(8*9)+(7*5)+(6*0)+(5*6)+(4*0)+(3*4)+(2*7)+(1*2)=165
165 % 10 = 5
So 950604-72-5 is a valid CAS Registry Number.
950604-72-5Relevant articles and documents
Systematic investigation of halogen bonding in protein-ligand interactions
Hardegger, Leo A.,Kuhn, Bernd,Spinnler, Beat,Anselm, Lilli,Ecabert, Robert,Stihle, Martine,Gsell, Bernard,Thoma, Ralf,Diez, Joachim,Benz, Joerg,Plancher, Jean-Marc,Hartmann, Guido,Banner, David W.,Haap, Wolfgang,Diederich, Francois
supporting information; experimental part, p. 314 - 318 (2011/02/28)
Halogen bonding triggers activity: Increasing binding affinity was observed for a series of covalent human Cathepsin L inhibitors by exchanging an aryl ring H atom with Cl, Br, and I, which undergo halogen bonding with the C=O group of Gly61 in the S3 pocket of the enzyme. Fluorine, in contrast, strongly avoids halogen bonding (see scheme). The strong distance and angle dependence of halogen bonding was confirmed for biological systems. Copyright
