951130-30-6

Basic information

• Product Name: 2-(5-methylfuran-2-yl)-1-phenylethyl propiolate
• Synonyms: 2-(5-methylfuran-2-yl)-1-phenylethyl propiolate
• CAS NO: 951130-30-6
• Molecular Weight: 202.253
• Mol File: 951130-30-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(5-methylfuran-2-yl)-1-phenylethyl propiolate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-methylfuran-2-yl)-1-phenylethyl propiolate(951130-30-6)
• EPA Substance Registry System: 2-(5-methylfuran-2-yl)-1-phenylethyl propiolate(951130-30-6)

Safety Data

• Hazardous Substances Data: 951130-30-6(Hazardous Substances Data)

Upstream product

• 534-22-5 2-methylfuran 
• 96-09-3 styrene oxide 

Downstream Products

• 1582305-76-7 8-hydroxy-7-methyl-3-phenylisochroman-1-one 
• 113503-02-9 2-(2-oxopropyl)-5-phenylfuran-3(2H)-one 
• 117203-31-3 2-(5-methylfuran-2-yl)-1-phenylethan-1-one 
• 1098067-05-0 C₁₃H₁₄O₃ 
• 951130-35-1 2-(2-prop-2-ynyloxy-2-phenylethyl)-5-methylfuran 

Relevant articles and documents

Gold catalysis: Biarylphosphine ligands as key for the synthesis of dihydroisocoumarins

Agold-catalyzed phenol synthesis was successfully used in the synthesis of dihydroisocoumarins for the first time.Alarge number of gold(I) complexes were prepared and tested; only complexes based on the biarylphosphine motif were successful. CSIRO 2014.

Singlet-oxygen-mediated one-pot synthesis of 3-keto-tetrahydrofurans from 2-(β-hydroxyalkyl) furans

(Chemical Equation Presented) Photooxygenation of 2-(β-hydroxyalkyl) furans affords, in one synthetic operation and in high yields, 3-keto-tetrhydrofuran motifs via intramolecular Michael-type addition to the 1,4-enedione intermediate.

Gold catalysis: Dihydroisobenzofurans and isochromanes by the intramolecular furan/alkyne reaction

A series of furyl alcohols and homofuryl alcohols was synthesized by reduction of furfurals or reaction of furyllithium compounds with epoxides and subsequent propargylation. The gold-catalyzed cycloisomerization of these products furnished dihydroisobenzofurans and isochromanes. Crystal structure analyses proved the sequence of the substituents for both classes of products. Unsaturated dicarbonyl compounds as side-products show the mechanistic relationship to the analogous platinum-catalyzed reactions. Neither ester groups, even on the 4-position of the furan ring, nor aryl bromides hinder the catalysis by gold. In the case of a substrate with an allyl ether in the side chain, a side-product, which provides evidence for a reaction of the alkyne with an inverse regioselectivity, was observed.