95203-11-5

Basic information

• Product Name: (2-Benzyl-4,5,6,7-tetrahydro-benzothiazol-6-yl)-methyl-amine
• Synonyms: (2-Benzyl-4,5,6,7-tetrahydro-benzothiazol-6-yl)-methyl-amine
• CAS NO: 95203-11-5
• Molecular Weight: 258.387
• Mol File: 95203-11-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-Benzyl-4,5,6,7-tetrahydro-benzothiazol-6-yl)-methyl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (2-Benzyl-4,5,6,7-tetrahydro-benzothiazol-6-yl)-methyl-amine(95203-11-5)
• EPA Substance Registry System: (2-Benzyl-4,5,6,7-tetrahydro-benzothiazol-6-yl)-methyl-amine(95203-11-5)

Safety Data

• Hazardous Substances Data: 95203-11-5(Hazardous Substances Data)

Upstream product

• 95203-05-7 2-Benzyl-4,7-dihydro-5H-benzothiazol-6-one 
• 74-89-5 methylamine 
• 6317-49-3 4-oxopimelate 
• 59742-68-6 diethyl 3-bromo-4-oxoheptanedioate 
• 95211-62-4 2-Benzyl-6-oxo-4,5,6,7-tetrahydro-benzothiazole-7-carboxylic acid ethyl ester 
• 95211-52-2 3-(2-Benzyl-5-ethoxycarbonylmethyl-thiazol-4-yl)-propionic acid ethyl ester 

Relevant articles and documents

Synthesis of aminoderivatives of 4,5,6,7-tetrahydro-benzothiazole. I. 4,5,6- and 7-amino and N-methyl amino derivatives with central dopaminergic activity

4-Oxo and 6-oxo-4,5,6,7-tetrahydro-benzothiazoles were prepared from diester derivatives of thiazole through Dieckmann cyclisation. The 7-oxo compound was synthesized by formation of a thiazole ring on 2-bromo-1,3-cyclohexanedione. The ketones were tranformed into amines and N-methylamines by reductive amination. The 5-amino derivatives were obtained by Hofmann reaction of the corresponding amides. The amines and N-methylamines in the 6-position have central dopaminergic properties. Their isomers in the 4, 5 or 7 positions are inactive.