95469-40-2

Basic information

• Product Name: Phenol, 4-[2-(dimethylamino)ethyl]-, acetate (ester)
• CAS NO: 95469-40-2
• Molecular Formula: C12H17NO2
• Molecular Weight: 207.272
• Mol File: 95469-40-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Phenol, 4-[2-(dimethylamino)ethyl]-, acetate (ester)(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-[2-(dimethylamino)ethyl]-, acetate (ester)(95469-40-2)
• EPA Substance Registry System: Phenol, 4-[2-(dimethylamino)ethyl]-, acetate (ester)(95469-40-2)

Safety Data

• Hazardous Substances Data: 95469-40-2(Hazardous Substances Data)

Upstream product

• 539-15-1 N,N-dimethyltyramine 
• 108-24-7 acetic anhydride 
• 52727-95-4 4-acetoxybenzyl bromide 
• 102101-52-0 (4-Acetoxy-benzyl)-dimethyl-trimethylsilanylmethyl-ammonium; bromide 

Downstream Products

• 109186-33-6 (4-acetoxy-phenethyl)-trimethyl-ammonium; iodide 

Relevant articles and documents

Selection of a Sommelet-Hauser or a Stevens Rearrangement Pathway of N,N-Dimethyl(substituted benzyl)ammonium N-Alkylides

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Rearrangement of (Substituted benzyl)trimethylammonium Ylides in a Nonbasic Medium: The Improved Sommelet-Hauser Rearrangement

Benzyl quaternary ammonium ylide formation in a nonbasic medium was accomplished by fluoride anion induced desilylation of benzyldimethylammonium bromide (3a) and ortho- or para-substituted benzyl analogues 3b-k.Treatment of 3 with CsF in HMPA at room temperature gives high yields of the Sommelet-Hauser rearrangement products 7 from 3a and methyl-, acetoxy-, and chloro-substituted analogues 3b-f.However, formation of the Stevens rearrangement products 8 is competitive for the reaction of compounds 3g-k having strong electron-withdrawing substituents such as acetyl, cyano, and nitrogen groups.From the o-cyano-substituted analogue 3h, a considerable amount of para Sommelet-Hauser rearrangement product is isolated.