955-77-1

Basic information

• Product Name: Benzoxazole, 5-chloro-2-(4-chlorophenyl)-
• CAS NO: 955-77-1
• Molecular Formula: C13H7Cl2NO
• Molecular Weight: 264.111
• Mol File: 955-77-1.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzoxazole, 5-chloro-2-(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoxazole, 5-chloro-2-(4-chlorophenyl)-(955-77-1)
• EPA Substance Registry System: Benzoxazole, 5-chloro-2-(4-chlorophenyl)-(955-77-1)

Safety Data

• Hazardous Substances Data: 955-77-1(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 95-85-2 2-hydroxy-5-chloro-aniline 
• 873-76-7 para-Chlorobenzyl alcohol 
• 95-55-6 2-amino-phenol 
• 122-01-0 4-chloro-benzoyl chloride 
• 17200-29-2 5-chloro-benzoxazole 
• 83392-36-3 methyl 3-(4-chlorophenyl)-3-oxopropanedithioate 
• 1404220-82-1 (E)-4-chloro-2-((4-chlorobenzylidene)amino)phenol 
• 1198184-09-6 4-chlorophenyl 1H-imidazole-1-sulfonate 
• 64073-85-4 4-chloro-2-{[(4-chlorophenyl)methylidene]amino}-phenol 
• 18206-72-9 4-chloro-N-(5-chloro-2-hydroxyphenyl)benzamide 

Relevant articles and documents

Iron(III) Chloride Mediated para-Selective C-H Functionalization: Access to C5-Chloro and C5,C7-Dichloro/Dianisyl Substituted 2-Arylbenzoxazoles

Iron(III) chloride mediated para-selective C?H chlorination and subsequent annulation of 2-amidophenol to synthesize C5- and C5, C7-chlorinated benzoxazoles was developed. Further, the oxidative cross-dehydrogenative coupling of amidophenol with anisole b

Use of Hypervalent Iodine in the Synthesis of Isomeric Dihydrooxazoles

[Figure not available: see fulltext.] A convenient synthesis of 2- and/or 3-oxazolines has been developed depending on the structure and stereochemistry of the starting amino alcohol. PhI(OAc)2 acted as oxidant on the intermediate imine, as sup

p-Toluenesulfonic acid-catalyzed metal-free formal [4?+?1] heteroannulation via N[sbnd]H/O[sbnd]H/S[sbnd]H functionalization: One-pot access to 2-aryl/hetaryl/alkyl benzazole derivatives

A concise and direct one-pot [4?+?1] synthetic strategy for the construction of 2-substituted benzazoles such as benzoxazoles and benzothiazoles has been disclosed in high yields (80–98%) by cascade coupling reaction of 2-amino(thio)phenols with β-oxodithioesters. The current approach enables N[sbnd]H/O[sbnd]H/S[sbnd]H functionalization in one-pot under solventless condition leading to diverse benzazoles without use of any external metal. A wide range of 2-amino(thio)phenols and β-oxodithioesters are compatible toward this transformation with excellent functional group tolerance. Furthermore, we preempt the wider implications of this novel strategy by demonstrating its compatibility toward versatile diversification of DNA Topoisomerase-II inhibitors.