95611-73-7

Basic information

• Product Name: (1R,1'S)-1-benzyl-3-N-1'-isopropyl-2'-hydroxyethyl-N-phenylethylamino-1-(4-methoxyphenyl)propan-1-ol
• CAS NO: 95611-73-7
• Molecular Weight: 461.645
• Mol File: 95611-73-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1R,1'S)-1-benzyl-3-N-1'-isopropyl-2'-hydroxyethyl-N-phenylethylamino-1-(4-methoxyphenyl)propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,1'S)-1-benzyl-3-N-1'-isopropyl-2'-hydroxyethyl-N-phenylethylamino-1-(4-methoxyphenyl)propan-1-ol(95611-73-7)
• EPA Substance Registry System: (1R,1'S)-1-benzyl-3-N-1'-isopropyl-2'-hydroxyethyl-N-phenylethylamino-1-(4-methoxyphenyl)propan-1-ol(95611-73-7)

Safety Data

• Hazardous Substances Data: 95611-73-7(Hazardous Substances Data)

Upstream product

• 2026-48-4 (S)-valinol 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 95611-60-2 (S)-3-1'-isopropyl-2'-hydroxyethylamino-1-(4-methoxyphenyl)propan-1-one 
• 95611-59-9 (S)-3-4'-isopropyl-1',3'-oxazolidino-1-(4-methoxyphenyl)propan-1-one 
• 6921-34-2 benzylmagnesium chloride 
• 73085-90-2 benzyltitanium triisopropoxide 

Relevant articles and documents

Highly Diastereoselective 1,5-Asymmetric Induction to 3-Oxazolidino-1-phenylpropan-1-ones by Using Organotitanium Triisopropoxides

The reaction of (S)-3-4'-isopropyl-1',3'-oxazolidino-1-phenylpropan-1-ones (1a, 1b) with 4 mol eq of various organotitanium triisopropoxides in ether at room temperature for 18-20 h gave 1-alkyl(or aryl)-3-N-alkyl(or arylmethyl)-N-1'-isopropyl-2'-hydroxyethylamino-1-phenylpropan-1-ols (2a-h) in good yields.This 1,5-asymmetric induction proceeded with extremly diastereoselectivity.The absolute configurations of 2d and 3d were determined by X-ray analysis.Keywords-absolute configuration; 1,5-asymmetric induction; chiral 1,3-oxazolidine; chiral phenylpropan-1-ol; chiral phenylpropan-1-one; diastereoselective; Grignard reagent; organolithium; organotitanium triisopropoxide; X-ray analysis