95648-81-0Relevant articles and documents
Method for preparing beta-sodium glycerophosphate
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Paragraph 0027; 0028; 0029; 0030; 0031, (2017/01/17)
The invention provides a method for preparing beta-sodium glycerophosphate. The method comprises the following steps of: (a) esterification and cyclization, namely heating a glycerinum and inorganic phosphate mixture to 120-150 DEG C for reaction to 120-168 hours; (b) hydrolysis, namely adding a proper amount of water and 30% of a sodium hydroxide solution, carrying out temperature reaction on the reaction liquid for 8-20 hours, sampling and detecting the content of inorganic phosphorus of the solution, adding a proper amount of magnesium oxide according to the detected content of the inorganic phosphorus, stirring the solution for 3-5 hours and filtering the solution; (c) devitrification, namely cooling filtrate to 20-30 DEG C, dripping ethanol, cooling the filtrate to 0-5 DEG C for devitrification for 12-28 hours, filtering the product and washing the solid with ethanol to obtain a crude product; and (d) refining, dissolving the obtained crude product with water, adding ethanol or methanol at 20-30 DEG C, cooling the solution to 0-5 DEG C, carrying out devitrification for 12-28 hours and filtering and washing to obtain a primary refined wet product.
