956576-66-2

Basic information

• Product Name: 4-ISOTHIOCYANATO-N-(5-METHYLISOXAZOL-3-YL)BENZENESULFONAMIDE
• Synonyms: 4-ISOTHIOCYANATO-N-(5-METHYLISOXAZOL-3-YL)BENZENESULFONAMIDE
• CAS NO: 956576-66-2
• Molecular Formula: C₁₁H₉N₃O₃S₂
• Molecular Weight: 295.33746
• Mol File: 956576-66-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-ISOTHIOCYANATO-N-(5-METHYLISOXAZOL-3-YL)BENZENESULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ISOTHIOCYANATO-N-(5-METHYLISOXAZOL-3-YL)BENZENESULFONAMIDE(956576-66-2)
• EPA Substance Registry System: 4-ISOTHIOCYANATO-N-(5-METHYLISOXAZOL-3-YL)BENZENESULFONAMIDE(956576-66-2)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 956576-66-2(Hazardous Substances Data)

Upstream product

• 723-46-6 sulfamethoxazole 
• 811-68-7 silver(I) trifluoromethanethiolate 

Downstream Products

• 1188491-11-3 C₂₂H₂₂N₆O₃S₂ 
• 1188491-20-4 C₂₄H₂₄N₆O₄S₂ 

Relevant articles and documents

Synthesis of thiocarbamoyl fluorides and isothiocyanates using CF3SiMe3 and elemental sulfur or AgSCF3 and KBr with amines

Reactions of thiocarbonyl fluoride derived from cheap, readily available, and widely used CF3SiMe3, elemental sulfur, and KF with secondary amines and primary amines at room temperature in THF provided a wide variety of thiocarbamoyl fluorides and isothiocyanates in moderate to excellent yields, respectively. The two reactions show broad substrate scope and good functional group tolerance. Moreover, AgSCF3 reacts with secondary/primary amines under KBr at room temperature, affording quantitative thiocarbamoyl fluorides/isothiocyanates, which feature late-stage application.